Jianping Fu, PhD
Professor of Mechanical Engineering
Professor of Cell and Developmental Biology
[email protected]

Available to mentor
Jianping Fu, PhD
Professor
  • About
  • Links
  • Center Memberships
  • Research Overview
  • Recent Publications
    • About

    My group's research interests lie at the nexus of bioengineering, biophysics, and biology. Specifically, we integrate micro/nanoengineering, single-cell technologies, and systems and synthetic biology methods with new discoveries of mechanobiology, epigenetics, and stem cell biology for advancing understanding of human development and cancer biology. In our research, we have made significant contributions to these research areas: stem cell bioengineering, developmental bioengineering, cell mechanics, mechanotransduction, micro/nanofluidics, and BioMEMS.

    Links
    • Integrated Biosystems and Biomechanics Laboratory
    Center Memberships
    • Center Member
      Center for Cell Plasticity and Organ Design
    • Center Member
      Biosciences Initiative
    • Center Member
      Center for Integrative Research in Critical Care
    Research Overview

    Mechanobiology, Stem Cell Biology, Developmental Biology, Bioengineering, BioMEMS

    Recent Publications See All Publications
    • Journal Article
      Derivation of human primordial germ cell-like cells in an embryonic-like culture.
      Esfahani SN, Zheng Y, Arabpour A, Irizarry AMR, Kobayashi N, Xue X, Shao Y, Zhao C, Agranonik NL, Sparrow M, Hunt TJ, Faith J, Lara MJ, Wu QY, Silber S, Petropoulos S, Yang R, Chien KR, Clark AT, Fu J. Nat Commun, 2024 Jan 2; 15 (1): 167 DOI:10.1038/s41467-023-43871-2
      PMID: 38167821
    • Journal Article
      Regulation of long-range BMP gradients and embryonic polarity by propagation of local calcium-firing activity.
      Lee HC, Oliveira NMM, Hastings C, Baillie-Benson P, Moverley AA, Lu H-C, Zheng Y, Wilby EL, Weil TT, Page KM, Fu J, Moris N, Stern CD. Nat Commun, 2024 Feb 17; 15 (1): 1463 DOI:10.1038/s41467-024-45772-4
      PMID: 38368410
    • Journal Article
      Bioengineering embryo models
      Xue X, Liu Y, Fu J. Nature Reviews Bioengineering, 1 - 19. DOI:10.1038/s44222-024-00241-x
    • Journal Article
      Criteria for the standardization of stem-cell-based embryo models.
      Martinez Arias A, Rivron N, Moris N, Tam P, Alev C, Fu J, Hadjantonakis A-K, Hanna JH, Minchiotti G, Pourquie O, Sheng G, Solnica Krezel L, Veenvliet JV, Warmflash A. Nat Cell Biol, 2024 Oct; 26 (10): 1625 - 1628. DOI:10.1038/s41556-024-01492-x
      PMID: 39223372
    • Preprint
      A transgene-free, human peri-gastrulation embryo model with trilaminar embryonic disc-, amnion- and yolk sac-like structures
      Sun S, Zheng Y, Kim YS, Zhong Z, Kobayashi N, Xue X, Liu Y, Zhou Z, Xu Y, Zhai J, Wang H, Fu J. bioRxiv, DOI:10.1101/2024.08.05.606556
    • Journal Article
      A human pluripotent stem cell-based somitogenesis model using microfluidics.
      Liu Y, Kim YS, Xue X, Miao Y, Kobayashi N, Sun S, Yan RZ, Yang Q, Pourquié O, Fu J. Cell Stem Cell, 2024 Aug 1; 31 (8): 1113 - 1126.e6. DOI:10.1016/j.stem.2024.06.004
      PMID: 38981471
    • Journal Article
      Substrate Rigidity Modulates Segmentation Clock Dynamics in Isolated Presomitic Mesoderm Cells.
      Sung C-Y, Kadiyala U, Blanchard O, Yourston L, Walker D, Li L, Fu J, Yang Q. bioRxiv, 2024 Jul 4; DOI:10.1101/2024.07.02.601712
      PMID: 39005461
    • Journal Article
      FAK, vinculin, and talin control mechanosensitive YAP nuclear localization.
      Holland EN, Fernández-Yagüe MA, Zhou DW, O'Neill EB, Woodfolk AU, Mora-Boza A, Fu J, Schlaepfer DD, García AJ. Biomaterials, 2024 Jul; 308: 122542 DOI:10.1016/j.biomaterials.2024.122542
      PMID: 38547833