
Available to mentor

Gabriel Corfas obtained an MSc in Biological Sciences from the University of Buenos Aires and a doctorate in Neurobiology from the Weizmann Institute of Science. During his postdoctoral training, first at Washington University in St. Louis, MO, and then at Harvard Medical School, he contributed to identifying and cloning the trophic factor Neuregulin 1 and its mechanism of action. In 1996 he obtained a faculty position at Harvard Medical School and Boston Children’s Hospital (BCH), eventually becoming a Professor of Neurology and Otolaryngology and director of basic research in Otolaryngology at BCH.
Since 2014 Corfas has been the Director of the Kresge Hearing Research Institute and associate chair for research for the Department of Otolaryngology and Head and Neck Surgery at the University of Michigan in Ann Arbor.
Dr. Corfas’s research focuses on the cellular and molecular mechanisms of nervous system development, plasticity, degeneration, and regeneration. Current efforts are devoted to identifying the mechanisms of noise-induced and age-related hearing loss and developing therapies for these prevalent disorders. The lab also investigates how social isolation alters brain structure and function.
For his work, Dr. Corfas has received many honors and awards, including a Klingenstein Fellowship in the Neurosciences, an Alfred P. Sloan Research Fellowship, an award from the EJLB Foundation, a Young and an Independent Investigator Award from NARSAD, as well as being elected secretary and treasurer of the Association for Research in Otolaryngology and a fellow of the American Association for the Advancement of Science.
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Center MemberKresge Hearing Research Institute
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Center MemberSamuel and Jean Frankel Cardiovascular Center
Molecular and cellular mechanisms of brain development and plasticity
Cellular and molecular mechanisms of inner ear development and function
Hearing loss and Balance disorders
Neuron-glia interactions
Mechanisms of peripheral neuropathies
Development of drugs for peripheral neuropathies
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Wallace G, Ji L, Cassinotti LR, Kachman M, Lyssiotis CA, Burant CF, Corfas G. 2025 Mar 26;PreprintLipidomics profiling identifies β-oxidation as a key process in noise-induced hearing loss.
DOI:10.1101/2025.03.25.645361 PMID: 40196644 -
Kostrikov S, Hjortkjaer J, Dau T, Corfas G, Liberman LD, Liberman MC. Hear Res, 2025 Feb; 456: 109172Journal ArticleA modiolar-pillar gradient in auditory-nerve dendritic length: A novel post-synaptic contribution to dynamic range?
DOI:10.1016/j.heares.2024.109172 PMID: PMC11772111 -
Zhou X, Chen J, Patel JS, Ran W, Li Y, Van RS, Ibrahim MMH, Zhao C, Gao Y, Rong J, Chaudhary AF, Li G, Hu J, Davenport AT, Daunais JB, Shao Y, Ran C, Collier TL, Haider A, Schuster DM, Levey AI, Wang L, Corfas G, Liang SH. Acta Pharmaceutica Sinica B, 2025 Jan 1;Journal ArticleImaging poly(ADP-ribose) polymerase-1 (PARP1) in vivo with 18F-labeled brain penetrant positron emission tomography (PET) ligand
DOI:10.1016/j.apsb.2025.05.020 -
Kostrikov S, Hjortkjaer J, Dau T, Corfas G, Liberman LD, Liberman MC. bioRxiv, 2024 Nov 4;Journal ArticleA modiolar-pillar gradient in auditory-nerve dendritic length: a novel post-synaptic contribution to dynamic range?
DOI:10.1101/2024.11.04.621861 PMID: PMC11580876 -
Corfas G. 2024 Nov 8;PresentationHidden Hearing Loss: Cellular/Molecular Mechanisms; Implications for Auditory Processing, and Potential Therapies
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Cassinotti LR, Ji L, Yuk MC, Desai AS, Cass ND, Amir ZA, Corfas G. JCI Insight, 2024 Oct 8; 9 (19):Journal ArticleHidden hearing loss in a Charcot-Marie-Tooth type 1A mouse model.
DOI:10.1172/jci.insight.180315 PMID: PMC11466197 -
Rogalla MM, Quass GL, Yardley H, Martinez-Voigt C, Ford AN, Wallace G, Dileepkumar D, Corfas G, Apostolides PF. 2024 Sep 13;PreprintPopulation coding of auditory space in the dorsal inferior colliculus persists with altered binaural cues.
DOI:10.1101/2024.09.13.612867 PMID: 39314270 -
Cassinotti LR, Ji L, Yuk MC, Desai AS, Cass ND, Amir ZA, Corfas G. 2024 Aug 15;PreprintHidden hearing loss in a Charcot-Marie-Tooth type 1A mouse model.
DOI:10.1101/2023.12.14.571732 PMID: 38168255
