Available to mentor
Gabriel Corfas obtained an MSc in Biological Sciences from the University of Buenos Aires and a doctorate in Neurobiology from the Weizmann Institute of Science. During his postdoctoral training, first at Washington University in St. Louis, MO, and then at Harvard Medical School, he contributed to identifying and cloning the trophic factor Neuregulin 1 and its mechanism of action. In 1996 he obtained a faculty position at Harvard Medical School and Boston Children’s Hospital (BCH), eventually becoming a Professor of Neurology and Otolaryngology and director of basic research in Otolaryngology at BCH.
Since 2014 Corfas has been the Director of the Kresge Hearing Research Institute and associate chair for research for the Department of Otolaryngology and Head and Neck Surgery at the University of Michigan in Ann Arbor.
Dr. Corfas’s research focuses on the cellular and molecular mechanisms of nervous system development, plasticity, degeneration, and regeneration. Current efforts are devoted to identifying the mechanisms of noise-induced and age-related hearing loss and developing therapies for these prevalent disorders. The lab also investigates how social isolation alters brain structure and function.
For his work, Dr. Corfas has received many honors and awards, including a Klingenstein Fellowship in the Neurosciences, an Alfred P. Sloan Research Fellowship, an award from the EJLB Foundation, a Young and an Independent Investigator Award from NARSAD, as well as being elected secretary and treasurer of the Association for Research in Otolaryngology and a fellow of the American Association for the Advancement of Science.
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Center MemberKresge Hearing Research Institute
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Center MemberSamuel and Jean Frankel Cardiovascular Center
Molecular and cellular mechanisms of brain development and plasticity
Cellular and molecular mechanisms of inner ear development and function
Hearing loss and Balance disorders
Neuron-glia interactions
Mechanisms of peripheral neuropathies
Development of drugs for peripheral neuropathies
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Cassinotti LR, Ji L, Yuk MC, Desai AS, Cass ND, Amir ZA, Corfas G. JCI Insight, 2024 Oct 8; 9 (19):Journal ArticleHidden hearing loss in a Charcot-Marie-Tooth type 1A mouse model.
DOI:10.1172/jci.insight.180315 PMID: 39178128 -
Cassinotti LR, Ji L, Yuk MC, Desai AS, Cass ND, Amir ZA, Corfas G. 2024 Aug 15;PreprintHidden hearing loss in a Charcot-Marie-Tooth type 1A mouse model.
DOI:10.1101/2023.12.14.571732 PMID: 38168255 -
Mire MM, Elesela S, Morris S, Corfas G, Rasky A, Lukacs NW. Viruses, 2024 Jun 4; 16 (6):Journal ArticleRespiratory Virus-Induced PARP1 Alters DC Metabolism and Antiviral Immunity Inducing Pulmonary Immunopathology.
DOI:10.3390/v16060910 PMID: 38932202 -
Ji L, Borges BC, Martel DT, Wu C, Liberman MC, Shore SE, Corfas G. PLoS Biol, 2024 Jun; 22 (6): e3002665Journal ArticleFrom hidden hearing loss to supranormal auditory processing by neurotrophin 3-mediated modulation of inner hair cell synapse density.
DOI:10.1371/journal.pbio.3002665 PMID: 38935589 -
2024 Apr 1;PresentationDepartment of Biological Chemistry Seminar Series
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2024 Apr 1;PresentationFundación Instituto Leloir
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Corfas G. 2024 Apr 1;PresentationInstituto de Fisiologia, Biologi Molecular y Neurociencias, Universidad de
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2024 Apr 1;PresentationInstituto de Investigaciones en Ingeniería Genética y Biología Molecular “Dr. Héctor N. Torres”