Kai Guo
Research Assistant Professor
Neurology
[email protected]

Available to mentor
Kai Guo
Research Assistant Professor
  • About
  • Qualifications
  • Recent Publications
    • About

    Dr. Guo’s research focuses on bioinformatics and systems biology approaches to identify pathogenic mechanisms underlying neurodegeneration. His research goal is to develop analytic systems and integrate multi-level omics data at the systems level to support team science initiatives in partnership with both basic and clinician scientists to understand disease mechanisms better and identify potential therapeutic targets for devastating neurologic diseases. His ongoing objectives for his independent career are to build upon his bioinformatics discoveries and expand his research as a team scientist by integrating multi-omics data from ALS and peripheral neuropathy animal models and human cohorts.

    Qualifications
    • Postdoc
      University of Michigan–Ann Arbor, Neurology, 2022
    • Postdoc
      University of North Dakota, Biomedical Sciences, 2020
    • PhD
      Huazhong Agricultural University, Wuhan
    Recent Publications See All Publications
    • Journal Article
      Correction: Obesity-induced neuroinflammation and cognitive impairment in young adult versus middle-aged mice.
      Henn RE, Elzinga SE, Glass E, Parent R, Guo K, Allouch AM, Mendelson FE, Hayes J, Webber-Davis I, Murphy GG, Hur J, Feldman EL. Immun Ageing, 2024 Feb 21; 21 (1): 16 DOI:10.1186/s12979-024-00422-7
      PMID: 38383401
    • Journal Article
      Correction: Obesity-induced neuroinflammation and cognitive impairment in young adult versus middle-aged mice.
      Henn RE, Elzinga SE, Glass E, Parent R, Guo K, Allouch AM, Mendelson FE, Hayes J, Webber-Davis I, Murphy GG, Hur J, Feldman EL. Immun Ageing, 2024 Feb 21; 21 (1): 16 DOI:10.1186/s12979-024-00422-7
      PMID: 38383401
    • Journal Article
      Transcriptomic profiling of sciatic nerves and dorsal root ganglia reveals site-specific effects of prediabetic neuropathy.
      Eid SA, Elzinga SE, Guo K, Hinder LM, Hayes JM, Pacut CM, Koubek EJ, Hur J, Feldman EL. Transl Res, 2024 Aug; 270: 24 - 41. DOI:10.1016/j.trsl.2024.03.009
      PMID: 38556110
    • Journal Article
      Transcriptomic profiling of sciatic nerves and dorsal root ganglia reveals site-specific effects of prediabetic neuropathy.
      Eid SA, Elzinga SE, Guo K, Hinder LM, Hayes JM, Pacut CM, Koubek EJ, Hur J, Feldman EL. Transl Res, 2024 Aug; 270: 24 - 41. DOI:10.1016/j.trsl.2024.03.009
      PMID: 38556110
    • Journal Article
      Gut microbiome correlates with plasma lipids in amyotrophic lateral sclerosis.
      Guo K, Figueroa-Romero C, Noureldein MH, Murdock BJ, Savelieff MG, Hur J, Goutman SA, Feldman EL. Brain, 2024 Feb 1; 147 (2): 665 - 679. DOI:10.1093/brain/awad306
      PMID: 37721161
    • Journal Article
      Gut microbiome correlates with plasma lipids in amyotrophic lateral sclerosis.
      Guo K, Figueroa-Romero C, Noureldein MH, Murdock BJ, Savelieff MG, Hur J, Goutman SA, Feldman EL. Brain, 2024 Feb 1; 147 (2): 665 - 679. DOI:10.1093/brain/awad306
      PMID: 37721161
    • Journal Article
      Age-related dysregulation of intestinal epithelium fucosylation is linked to an increased risk of colon cancer.
      Wang Z, Gao P, Guo K, Schirrick G, Gill JS, Weis J, Lund Da Costa A, Rahman M, Mehta H, Fleecs J, Jain S, Debnath T, Hur J, Khan N, Sticca R, Brown-Borg HM, Jurivich DA, Mathur R. JCI Insight, 2024 Mar 8; 9 (5): DOI:10.1172/jci.insight.167676
      PMID: 38456503
    • Journal Article
      Age-related dysregulation of intestinal epithelium fucosylation is linked to an increased risk of colon cancer.
      Wang Z, Gao P, Guo K, Schirrick G, Gill JS, Weis J, Lund Da Costa A, Rahman M, Mehta H, Fleecs J, Jain S, Debnath T, Hur J, Khan N, Sticca R, Brown-Borg HM, Jurivich DA, Mathur R. JCI Insight, 2024 Mar 8; 9 (5): DOI:10.1172/jci.insight.167676
      PMID: 38456503