Available to mentor
Elisabeth Pedersen MD, PhD is an Assistant Professor of Dermatology on the tenure track. Dr. Pedersen is a physician-scientist building a research program focused on understanding the mechanisms of cellular behavior within the tumor microenvironment, in basal cell carcinoma and other skin cancers, located in the Rogel Cancer Center. She sees patients in the Multidisciplinary Cutaneous Oncology clinic at the Taubman Center and Rogel Cancer Center.
Dr. Pedersen's research interests include understanding carcinogenesis and tumor progression through a lens of developmental biology. She is investigating how normal and malignant cells in the tumor microenvironment interact to promote tumor progression. In particular, she is studying the role of melanocytes in the tumor microenvironment and how their behavior mimics normal hair follicle biology. She is also pursuing developing preclinical models to better study rare cancers and sarcomas including dermatofibrosarcoma protuberans.
Dr. Pedersen is currently investigating how normal and malignant cells in the tumor microenvironment interact to promote tumor progression. She is also developing preclinical models to better study rare sarcomas including dermatofibrosarcoma protuberans.
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Wenzel D, Schuler AM, Smith DC, Evans JR, Harms KL, Pedersen EA. JAAD Case Rep, 2024 Oct; 52: 112 - 115.Journal ArticleCirculating tumor DNA is a useful adjunct for Merkel cell carcinoma monitoring in the context of multiple metastatic malignancies.
DOI:10.1016/j.jdcr.2024.07.026 PMID: 39385809 -
Pedersen E. 2024 Jun 7;PresentationBeyond the Basics: Advanced Treatments of Non-Melanoma Cancer
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Durgin JS, Whittington CP, Joseph M, Harms PW, Andea AA, Pedersen EA, Smith EH, Harms KL. J Cutan Pathol, 2024 Jul; 51 (7): 490 - 495.Journal ArticleMultiple primary dermatofibrosarcoma protuberans tumors in a single patient with chromosomal microarray analysis: A case report and review.
DOI:10.1111/cup.14612 PMID: 38548658 -
Pedersen E. 2024 Apr 10;PresentationUnderstanding Pigmentation in Basal Cell Carcinoma
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Pedersen EA, Fisher GJ, Voorhees JJ, Sachs DL. 2024 Apr; Rook's Textbook of Dermatology,ChapterSkin Ageing
DOI:10.1002/9781119709268.rook156 -
Negris O, Chan M, Harms K, Pedersen E. 2024 Mar 9;PresentationA rare case of sweat gland carcinoma of the scalp with neuroendocrine differentiation – primary cutaneous malignancy or breast cancer metastasis?
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Pedersen EA, Verhaegen ME, Joseph MK, Harms KL, Harms PW. Front Oncol, 2024 14: 1413793Journal ArticleMerkel cell carcinoma: updates in tumor biology, emerging therapies, and preclinical models.
DOI:10.3389/fonc.2024.1413793 PMID: 39136002 -
Pedersen EA, Grachtchouk MA, Verhaegen ME, Syu L, Harms PW, Gharaee-Kermani M, Ma F, Gudjonsson J, Ito M, Dlugosz A. Journal of Investigative Dermatology, 2023 May; 143 (5): s220Proceeding / Abstract / Poster1282 Basal cell carcinoma pigmentation is associated with melanocyte proliferation and expression of the melanocyte mitogens endothelin 1 and 2 by tumor cells
DOI:10.1016/j.jid.2023.03.1296