Jun Gao
Research Investigator
Internal Medicine
Int Med-Gastroenterology
1150 west medical center dr, MSRB3 9315
Ann Arbor, Michigan 48109
[email protected]

Available to mentor
Jun Gao
Research Investigator
  • About
  • Qualifications
  • Research Overview
  • Recent Publications
    • About

    Jun Gao holds a Ph.D. in Gastroenterology. In 2018, he joined the University of Michigan as a Research Lab Specialist Intermediate and transitioned to a Research Investigator role in 2022. His research focuses on the crosstalk between commensal bacteria and tryptophan hydroxylase in the serotonin system of the gut.

    Qualifications
    • Research fellow
      University of Michigan Medical School, Int Med-Gastroenterology, 2015
    • Research fellow
      University of Michigan Medical School, Int Med-Gastroenterology, 2004
    • Ph.D.
      Second Military Medical University, Department of Internal Medicine, Changhai Hospital, 2005
    • M.D.
      Second Military Medical University, Shanghai, 1999
    Research Overview

    The cross talk between commensal bacteria and tryptophan hydroxylase of the serotonin system in the gut.

    Recent Publications See All Publications
    • Proceeding / Abstract / Poster
      FECAL LPS CAUSES FODMAP-MEDIATED BARRIER DYSFUNCTION IN IBS-D VIA TLR4-DEPENDENT MAST-CELL ACTIVATION
      Singh P, Gao J, Owyang C. GASTROENTEROLOGY, 2023 May 8; 164 (6): S166 - S167.
    • Proceeding / Abstract / Poster
      THE LUMINAL MICROBIOME REGULATES GLUTAMINE SYNTHETASE LEVELS IN A SUBSET OF PATIENTS WITH DIARRHEA-PREDOMINANT IRRITABLE BOWEL SYNDROME LEADING TO BARRIER DYSFUNCTION
      Singh P, Gao J, Owyang C. GASTROENTEROLOGY, 2023 May 8; 164 (6): S166 - S166.
    • Journal Article
      Mucosal Serotonin Reuptake Transporter Expression in Irritable Bowel Syndrome Is Modulated by Gut Microbiota Via Mast Cell-Prostaglandin E2.
      Gao J, Xiong T, Grabauskas G, Owyang C. Gastroenterology, 2022 Jun; 162 (7): 1962 - 1974.e6. DOI:10.1053/j.gastro.2022.02.016
      PMID: 35167867
    • Proceeding / Abstract / Poster
      GRAM plus VE BACTERIA ACTIVATES MACROPHAGE TLR2 TO UPREGULATE MUCOSAL DUOX2 BY AN IL1B PATHWAY
      Gao J, Grabauskas G, Wu X, Singh P, Chung O. GASTROENTEROLOGY, 2022 May 23; 162 (7): S1009 - S1009.
    • Journal Article
      Upregulation of acid sensing ion channels is associated with esophageal hypersensitivity in GERD.
      Han X, Zhang Y, Lee A, Li Z, Gao J, Wu X, Zhao J, Wang H, Chen D, Zou D, Owyang C. FASEB J, 2022 Jan; 36 (1): e22083 DOI:10.1096/fj.202100606R
      PMID: 34918385
    • Journal Article
      High FODMAP diet causes barrier loss via lipopolysaccharide-mediated mast cell activation.
      Singh P, Grabauskas G, Zhou S-Y, Gao J, Zhang Y, Owyang C. JCI Insight, 2021 Nov 22; 6 (22): DOI:10.1172/jci.insight.146529
      PMID: 34618688
    • Proceeding / Abstract / Poster
      DIETARY MONOSODIUM GLUTAMATE (MSG) ACTS ON TAS1R1/TAS1R3 EXPRESSING GASTRIC TUFT CELLS TO STIMULATE ATP RELEASE AND INDUCE VISCERAL HYPERSENSITIVITY
      Zhang Y, Grabauskas G, Wu X, Gao J, Owyang C. GASTROENTEROLOGY, 2021 May 21; 160 (6): S487 - S487.
    • Proceeding / Abstract / Poster
      FERMENTATION PRODUCT PROPIONIC ACID PRODUCED BY SPECIFIC GUT BACTERIA INDUCES BARRIER DYSFUNCTION AND SUBCLINICAL MUCOSA INFLAMMATION
      Zhang Y, Gao J, Zhou S-Y, Chen B, Dai N, Wang X, Owyang C. GASTROENTEROLOGY, 2021 May 21; 160 (6): S565 - S565.