Charles Matrosic, PhD
Clinical Assistant Professor of Radiation Oncology
Department of Radiation Oncology - Michigan Medicine
1500 E. Medical Center Drive
Ann Arbor, Michigan 48103-5010
[email protected]

Available to mentor

Charles Matrosic, PhD
Clinical Assistant Professor
  • Qualifications
  • Research Overview
  • Recent Publications
  • Qualifications
    • Ph.D., Medical Physics “Development of a liver gel-dosimetry motion phantom for real-time image-guided radiotherapy verification"
      University of Wisconsin, Madison, Wisconsin, 2019
    • M.S., Medical Physics
      University of Wisconsin, Madison, Wisconsin, 2016
    • B.S.E., Nuclear Engineering and Radiological Sciences – Physics Minor, Summa Cum Laude
      University of Michigan, Ann Arbor, Michigan, 2014
    Research Overview

    Clinical Interests:
    • External Beam Radiotherapy Treatment Planning: I am regularly involved in physics treatment plan checks to ensure treatment quality and safety and am a member of the Dosimetry Affinity Group. I am also the physics co-lead of the lung treatment site and help improve treatment planning procedures and documentation for the site.
    • Special Medical Physics Consultation (SMPC): I regularly cover SMPCs for patient retreatment cases, which involves estimating patient dose sums based on potential repair of damage from previous treatments and estimating new healthy tissue dose limits based on these dose sums.
    • Brachytherapy: I am a member of my department’s Brachytherapy Affinity Group, participate regularly in HDR treatments, and am the lead physicist for the I-125 Eye Plaque service at the University of Michigan Department of Radiation Oncology.

    Research Interests:
    • Functional lung imaging and implementation of function-guided treatment planning into the management of lung cancer radiotherapy
    • The implementation of knowledge-based planning as a quality assurance tool in radiotherapy treatment planning
    • The implementation of advanced radiotherapy treatment planning techniques into clinical practice

    Recent Publications See All Publications
    • Presentation
      Workflow and Approaches to Evaluation of Dose and Treatment Planning for Re-Irradiation Cases
      Matrosic C. 2023 Oct 1;
    • Journal Article
      Knowledge-Based Quality Assurance and Model Maintenance in Lung Cancer Radiation Therapy in a Statewide Quality Consortium of Academic and Community Practice Centers.
      Matrosic CK, Dess K, Boike T, Dominello M, Dryden D, Fraser C, Grubb M, Hayman J, Jarema D, Marsh R, Paximadis P, Torolski K, Wilson M, Jolly S, Matuszak M, Michigan Radiation Oncology Quality Consortium . Pract Radiat Oncol, 2023 13 (2): e200 - e208. DOI:10.1016/j.prro.2022.11.009
      PMID: 36526245
    • Journal Article
      Direct incorporation of patient-specific efficacy and toxicity estimates in radiation therapy plan optimization.
      Polan DF, Epelman MA, Wu VW, Sun Y, Varsta M, Owen DR, Jarema D, Matrosic CK, Jolly S, Schonewolf CA, Schipper MJ, Matuszak MM. Med Phys, 2022 Oct; 49 (10): 6279 - 6292. DOI:10.1002/mp.15940
      PMID: 35994026
    • Additional Scholarship
      Commissioning Report: Sun Nuclear Stereotactic radiosurgery mapcheck
      Matrosic C, Roberts D, Prisciandaro J. 2022
    • Journal Article
      Feasibility of function-guided lung treatment planning with parametric response mapping.
      Matrosic CK, Owen DR, Polan D, Sun Y, Jolly S, Schonewolf C, Schipper M, Haken RKT, Galban CJ, Matuszak M. J Appl Clin Med Phys, 2021 Nov; 22 (11): 80 - 89. DOI:10.1002/acm2.13436
      PMID: 34697884
    • Journal Article
      First-in-human imaging using a MR-compatible e4D ultrasound probe for motion management of radiotherapy.
      Bednarz BP, Jupitz S, Lee W, Mills D, Chan H, Fiorillo T, Sabitini J, Shoudy D, Patel A, Mitra J, Sarcar S, Wang B, Shepard A, Matrosic C, Holmes J, Culberson W, Bassetti M, Hill P, McMillan A, Zagzebski J, Smith LS, Foo TK. Phys Med, 2021 Aug; 88: 104 - 110. DOI:10.1016/j.ejmp.2021.06.017
      PMID: 34218199
    • Journal Article
      3D dosimetric validation of ultrasound-guided radiotherapy with a dynamically deformable abdominal phantom.
      Matrosic CK, Culberson W, Shepard A, Jupitz S, Bednarz B. Phys Med, 2021 Apr; 84: 159 - 167. DOI:10.1016/j.ejmp.2021.04.007
      PMID: 33901860
    • Proceeding / Abstract / Poster
      BEST IN PHYSICS (MULTI-DISCIPLINARY): Lung Treatment Planning with Parametric Response Mapping Function Guidance
      Matrosic CK, Owen DR, Polan D, Sun Y, Jolly S, Schonewolf C, Schipper M, Ten Haken R, Galban C, Matuszak M. MEDICAL PHYSICS, 2021 48 (6):