Research Investigator
Internal Medicine
[email protected]
Available to mentor
Lei Yu
Research Investigator
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PhDTohoku University, Sendai, 2015
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Master of ScienceChina Agricultural University, Beijing, 2009
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Bachelor of ScienceQingdao University of Science and Technology, Qingdao, 2006
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Wang Y, Myers G, Yu L, Deng K, Balbin-Cuesta G, Singh SA, Guan Y, Khoriaty R, Engel JD. Blood, 2024 Oct 11;Journal ArticleTR4 and BCL11A Repress γ-globin Transcription via Independent Mechanisms.
DOI:10.1182/blood.2024024599 PMID: 39393056 -
Myers G, Wang Y, Wang Q, Friedman A, Sanchez-Martinez A, Liu X, Singh SA, Lim K-C, Khoriaty R, Engel JD, Yu L. Blood Adv, 2023 Oct 10; 7 (19): 5727 - 5732.Journal ArticleMurine erythroid differentiation kinetics in vivo under normal and anemic stress conditions.
DOI:10.1182/bloodadvances.2023010088 PMID: 37552129 -
Yu L, Myers G, Schneider E, Wang Y, Mathews R, Lim KC, Siemieniak D, Tang V, Ginsburg D, Balbin-Cuesta G, Singh SA, Phuwakanjana P, Jearawiriyapaisarn N, Khoriaty R, Engel JD. Blood Adv, 2022 Jun 14; 6 (11): 3280 - 3285.Journal ArticleIdentification of novel γ-globin inducers among all potential erythroid druggable targets.
DOI:10.1182/bloodadvances.2021006802 PMID: 35240686 -
Yu L, Myers G, Ku C-J, Schneider E, Wang Y, Singh SA, Jearawiriyapaisarn N, White A, Moriguchi T, Khoriaty R, Yamamoto M, Rosenfeld MG, Pedron J, Bushweller JH, Lim K-C, Engel JD. Blood, 2021 Nov 4; 138 (18): 1691 - 1704.Journal ArticleAn erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation.
DOI:10.1182/blood.2021011682 PMID: 34324630 -
Yu L, Lemay P, Ludlow A, Guyot M-C, Jones M, Mohamed FF, Saroya G-A, Panaretos C, Schneider E, Wang Y, Myers G, Khoriaty R, Li Q, Franceschi R, Engel JD, Kaartinen V, Rothstein TL, Justice MJ, Kibar Z, Singh SA. Blood Advances, 2021 Oct 26; 5 (20): 4167 - 4179.Journal ArticleA new murine Rpl5 (uL18) mutation provides a unique model of variably penetrant Diamond Blackfan Anemia
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Himadewi P, Wang XQD, Feng F, Gore H, Liu Y, Yu L, Kurita R, Nakamura Y, Pfeifer GP, Liu J, Zhang X. Elife, 2021 Sep 29; 10:Journal Article3'HS1 CTCF binding site in human β-globin locus regulates fetal hemoglobin expression.
DOI:10.7554/eLife.70557 PMID: 34585664 -
Himadewi P, Wang XQD, Feng F, Gore H, Liu Y, Yu L, Liu J, Kurita R, Nakamura Y, Pfeifer G, Zhang X. bioRxiv,Preprint3’HS1 CTCF binding site in human β-globin locus regulates fetal hemoglobin expression
DOI:10.1101/2021.05.18.444713 -
Yu L, Lemay P, Ludlow A, Guyot M-C, Jones M, Mohamed F, Saroya G-A, Panaretos C, Schneider E, Wang Y, Myers G, Khoriaty R, Li Q, Franceschi R, Engel JD, Kaartinen V, Rothstein T, Justice M, Kibar Z, Singh S. 2021 bioRxiv,PreprintA new murine<i>Rpl5</i>(<i>uL18</i>) mutation provides a unique model of variably penetrant Diamond Blackfan Anemia
DOI:10.1101/2021.02.27.430069