Research Assistant Professor
Internal Medicine
Internal Medicine
2800 Plymouth Road
Ann Arbor, Michigan 48109
[email protected]
2800 Plymouth Road
Ann Arbor, Michigan 48109
Available to mentor
Xiaoqiang Huang
Research Assistant Professor
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Postdoctoral FellowUniversity of Michigan–Ann Arbor, Computational Medicine and Bioinformatics, 2020
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PhDTsinghua University, Beijing, 2017
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MSTsinghua University, Beijing, 2014
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BSTsinghua University, Beijing, 2010
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Center MemberSamuel and Jean Frankel Cardiovascular Center
computational protein design; enzyme design; protein engineering
My Google Scholar profile
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Woodard J, Huang X. Sci Bull (Beijing), 2024 May 30; 69 (10): 1367 - 1368.Journal ArticleDeep learning-powered enzyme efficiency boosting with evolutionary information.
DOI:10.1016/j.scib.2024.03.034 PMID: 38531716 -
Huang X, Sun Y, Osawa Y, Chen YE, Zhang H. J Biol Chem, 2023 Aug; 299 (8): 105050Journal ArticleComputational redesign of cytochrome P450 CYP102A1 for highly stereoselective omeprazole hydroxylation by UniDesign.
DOI:10.1016/j.jbc.2023.105050 PMID: 37451479 -
Sun Y, Huang X, Osawa Y, Chen YE, Zhang H. Molecules, 2023 Jul 12; 28 (14):Journal ArticleThe Versatile Biocatalyst of Cytochrome P450 CYP102A1: Structure, Function, and Engineering.
DOI:10.3390/molecules28145353 PMID: 37513226 -
Li Z, Huang X, Li M, Chen YE, Wang Z, Liu L. Heliyon, 2023 May; 9 (5): e16318Journal ArticleA ubiquitination-mediated degradation system to target 14-3-3-binding phosphoproteins.
DOI:10.1016/j.heliyon.2023.e16318 PMID: 37251884 -
Huang X, Zhou J, Yang D, Zhang J, Xia X, Chen YE, Xu J. Brief Bioinform, 2023 May 19; 24 (3):Journal ArticleDecoding CRISPR-Cas PAM recognition with UniDesign.
DOI:10.1093/bib/bbad133 PMID: 37078688 -
Huang X, Wu H, Zhong W, Li W, Liu Z, Zhao M, Xi X, Cao B, Pu Y, Kong X, Zhao H, Zhang R, Lai K, Lv X, Lv Y, Bao J, Wang M, Xiong Y, Dong L, Zhang J, Zhang G, Hu Y, Xu J, Chen YE, Chen S. bioRxiv,PreprintDiscovery of microsized RNA-derived RNAs and proteins in human cells
DOI:10.1101/2023.04.24.538138 -
Pearce R, Huang X, Omenn GS, Zhang Y. Proc Natl Acad Sci U S A, 2023 Jan 24; 120 (4): e2208275120Journal ArticleDe novo protein fold design through sequence-independent fragment assembly simulations.
DOI:10.1073/pnas.2208275120 PMID: 36656852 -
Huang X, Yang D, Zhang J, Xu J, Chen YE. Cells, 2022 Jul 13; 11 (14):Journal ArticleRecent Advances in Improving Gene-Editing Specificity through CRISPR-Cas9 Nuclease Engineering.
DOI:10.3390/cells11142186 PMID: 35883629