Xiaoqiang Huang
Research Assistant Professor
Internal Medicine
Internal Medicine
2800 Plymouth Road
Ann Arbor, Michigan 48109
[email protected]

Available to mentor

Xiaoqiang Huang
Research Assistant Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Links
  • Recent Publications
  • Qualifications
    • Postdoctoral Fellow
      University of Michigan–Ann Arbor, Computational Medicine and Bioinformatics, 2020
    • PhD
      Tsinghua University, Beijing, 2017
    • MS
      Tsinghua University, Beijing, 2014
    • BS
      Tsinghua University, Beijing, 2010
    Center Memberships
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    Research Overview

    computational protein design; enzyme design; protein engineering

    Links
    • My Google Scholar profile
    Recent Publications See All Publications
    • Journal Article
      Deep learning-powered enzyme efficiency boosting with evolutionary information.
      Woodard J, Huang X. Sci Bull (Beijing), 2024 May 30; 69 (10): 1367 - 1368. DOI:10.1016/j.scib.2024.03.034
      PMID: 38531716
    • Journal Article
      Computational redesign of cytochrome P450 CYP102A1 for highly stereoselective omeprazole hydroxylation by UniDesign.
      Huang X, Sun Y, Osawa Y, Chen YE, Zhang H. J Biol Chem, 2023 Aug; 299 (8): 105050 DOI:10.1016/j.jbc.2023.105050
      PMID: 37451479
    • Journal Article
      The Versatile Biocatalyst of Cytochrome P450 CYP102A1: Structure, Function, and Engineering.
      Sun Y, Huang X, Osawa Y, Chen YE, Zhang H. Molecules, 2023 Jul 12; 28 (14): DOI:10.3390/molecules28145353
      PMID: 37513226
    • Journal Article
      A ubiquitination-mediated degradation system to target 14-3-3-binding phosphoproteins.
      Li Z, Huang X, Li M, Chen YE, Wang Z, Liu L. Heliyon, 2023 May; 9 (5): e16318 DOI:10.1016/j.heliyon.2023.e16318
      PMID: 37251884
    • Journal Article
      Decoding CRISPR-Cas PAM recognition with UniDesign.
      Huang X, Zhou J, Yang D, Zhang J, Xia X, Chen YE, Xu J. Brief Bioinform, 2023 May 19; 24 (3): DOI:10.1093/bib/bbad133
      PMID: 37078688
    • Preprint
      Discovery of microsized RNA-derived RNAs and proteins in human cells
      Huang X, Wu H, Zhong W, Li W, Liu Z, Zhao M, Xi X, Cao B, Pu Y, Kong X, Zhao H, Zhang R, Lai K, Lv X, Lv Y, Bao J, Wang M, Xiong Y, Dong L, Zhang J, Zhang G, Hu Y, Xu J, Chen YE, Chen S. bioRxiv, DOI:10.1101/2023.04.24.538138
    • Journal Article
      De novo protein fold design through sequence-independent fragment assembly simulations.
      Pearce R, Huang X, Omenn GS, Zhang Y. Proc Natl Acad Sci U S A, 2023 Jan 24; 120 (4): e2208275120 DOI:10.1073/pnas.2208275120
      PMID: 36656852
    • Journal Article
      Recent Advances in Improving Gene-Editing Specificity through CRISPR-Cas9 Nuclease Engineering.
      Huang X, Yang D, Zhang J, Xu J, Chen YE. Cells, 2022 Jul 13; 11 (14): DOI:10.3390/cells11142186
      PMID: 35883629