Assistant Research Scientist
Internal Medicine
[email protected]
Available to mentor
Mi Wang
Assistant Research Scientist
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Xu R, Zhou H, Bai L, McEachern D, Wu D, Acharyya RK, Wang M, Tošović J, Yang C-Y, Chinnaswamy K, Meagher JL, Stuckey JA, Liu C, Wang M, Wen B, Sun D, Wang S. J Med Chem, 2024 Nov 28; 67 (22): 20495 - 20513.Journal ArticleDiscovery of SD-436: A Potent, Highly Selective and Efficacious STAT3 PROTAC Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression.
DOI:10.1021/acs.jmedchem.4c01946 PMID: 39509603 -
Wang C, Wang M, Wang Y, Rej RK, Aguilar A, Xu T, Bai L, Tošović J, McEachern D, Li Q, Sarkari F, Wen B, Sun D, Wang S. J Med Chem, 2024 Aug 22; 67 (16): 14125 - 14154.Journal ArticleDiscovery of CW-3308 as a Potent, Selective, and Orally Efficacious PROTAC Degrader of BRD9.
DOI:10.1021/acs.jmedchem.4c00971 PMID: 39132814 -
Chen Z, Wang M, Wu D, Bai L, Xu T, Metwally H, Wang Y, McEachern D, Zhao L, Li R, Takyi-Williams J, Wang M, Wang L, Li Q, Wen B, Sun D, Wang S. J Med Chem, 2024 Apr 11; 67 (7): 5275 - 5304.Journal ArticleDiscovery of CBPD-268 as an Exceptionally Potent and Orally Efficacious CBP/p300 PROTAC Degrader Capable of Achieving Tumor Regression.
DOI:10.1021/acs.jmedchem.3c02124 PMID: 38477974 -
Chen Z, Wang M, Wu D, Zhao L, Metwally H, Jiang W, Wang Y, Bai L, McEachern D, Luo J, Wang M, Li Q, Matvekas A, Wen B, Sun D, Chinnaiyan AM, Wang S. J Med Chem, 2024 Apr 11; 67 (7): 5351 - 5372.Journal ArticleDiscovery of CBPD-409 as a Highly Potent, Selective, and Orally Efficacious CBP/p300 PROTAC Degrader for the Treatment of Advanced Prostate Cancer.
DOI:10.1021/acs.jmedchem.3c01789 PMID: 38530938 -
Kaneshige A, Yang Y, Bai L, Wang M, Xu R, Mallik L, Chinnaswamy K, Metwally H, Wang Y, McEachern D, Tošović J, Yang C-Y, Kirchhoff PD, Meagher JL, Stuckey JA, Wang S. J Med Chem, 2024 Sep 23;Journal ArticleDiscovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader.
DOI:10.1021/acs.jmedchem.4c01009 PMID: 39311434 -
Li Z, Harikrishnan LS, Xu G, Samanta D, Clemente JC, Leng L, Tu W, Yang L, Huang L, Wang M, Wang S, Deng Q, Behshad E, Nagilla R, Orth P, Rice C, Strickland C, Mohammad HP, Priestley ES, Sui Z. J Med Chem, 2024 Nov 21;Journal ArticleDiscovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders.
DOI:10.1021/acs.jmedchem.4c01878 PMID: 39570797 -
Zheng C, Rej RK, Wang M, Huang L, Fernandez-Salas E, Yang C-Y, Wang S. ACS Med Chem Lett, 2023 Oct 12; 14 (10): 1389 - 1395.Journal ArticleDiscovery of Pyrrolo[2,3-c]pyridines as Potent and Reversible LSD1 Inhibitors.
DOI:10.1021/acsmedchemlett.3c00292 PMID: 37849536 -
Xiang W, Zhao L, Han X, Xu T, Kregel S, Wang M, Miao B, Qin C, Wang M, McEachern D, Lu J, Bai L, Yang C-Y, Kirchhoff PD, Takyi-Williams J, Wang L, Wen B, Sun D, Ator M, Mckean R, Chinnaiyan AM, Wang S. J Med Chem, 2023 Sep 28; 66 (18): 13280 - 13303.Journal ArticleDiscovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer.
DOI:10.1021/acs.jmedchem.3c01264 PMID: 37683104
