Max S Wicha, MD
Madeline and Sidney Forbes Professor of Oncology and Professor of Internal Medicine
[email protected]

Available to mentor
Max S Wicha, MD
Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
    • Qualifications
    • Biology Degree
      State University of NY at Stony Brook, United States, 1970
    Center Memberships
    • Center Member
      Rogel Cancer Center
    • Center Member
      Taubman Institute
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      MM-PKUHSC Joint Institute
    • Center Member
      Biointerfaces Institute
    • Center Member
      Center for Cell Plasticity and Organ Design
    • Center Member
      Global REACH
    Research Overview

    Mammary cell biology
    * Regulation of mammary growth, differentiation and apoptosis
    * Stem cells in normal mammary development and breast cancer
    * Cancer stem cell therapeutics

    Recent Publications See All Publications
    • Journal Article
      Simultaneous Targeting of NQO1 and SOD1 Eradicates Breast Cancer Stem Cells via Mitochondrial Futile Redox Cycling.
      Luo M, Shen N, Shang L, Fang Z, Xin Y, Ma Y, Du M, Yuan Y, Hu C, Tang Y, Huang J, Wei W, Lee MR, Hergenrother PJ, Wicha MS. Cancer Res, 2024 Sep 12; DOI:10.1158/0008-5472.CAN-24-0800
      PMID: 39264695
    • Preprint
      SLC4A11 mediates ammonia import and promotes cancer stemness in hepatocellular carcinoma
      Elaimy AL, El-Derany MO, James J, Wang Z, Pearson AN, Holcomb EA, Huber AK, Gijón M, Bell HN, Sanghvi VR, Frankel TL, Su GL, Tapper EB, Tai AW, Ramnath N, Centonze CP, Dobrosotskaya I, Moeller JA, Bryant AK, Elliott DA, Choi E, Evans JR, Cuneo KC, Fitzgerald TJ, Wahl DR, Morgan MA, Chang DT, Wicha MS, Lawrence TS, Shah YM, Green MD. bioRxiv, DOI:10.1101/2024.08.06.606899
    • Journal Article
      Natural Killer Cell Regulation of Breast Cancer Stem Cells Mediates Metastatic Dormancy.
      Bushnell GG, Sharma D, Wilmot HC, Zheng M, Fashina TD, Hutchens CM, Osipov S, Burness M, Wicha MS. Cancer Res, 2024 Aug 6; DOI:10.1158/0008-5472.CAN-24-0030
      PMID: 39106452
    • Journal Article
      Abstract 2788: Immunological targeting of integrin β1high/β3high melanoma
      Wang F, Xin Y, Moon JJ, Chang AE, Wicha M, Li Q. Cancer Research, 2024 Mar 22; 84 (6_Supplement): 2788 - 2788. DOI:10.1158/1538-7445.am2024-2788
    • Journal Article
      Abstract A060: Organoid Culture as a Unique Resource for Studying Aggressive Triple Negative Breast Cancer in African American
      Kamita M, Fernando K, Antwi S, Amponsah-Manu F, Nsaful J, Akakpo K, Bensenhaver J, Agbedinu K, Nortey M, Affram N, Sheriff M, Mills C, Mremi A, Aja J, Dokurugu M, Ali H, Walker E, Wicha M, Jiagge E. Cancer Research, 2024 Feb 1; 84 (3_Supplement_1): a060 - a060. DOI:10.1158/1538-7445.advbc23-a060
    • Journal Article
      Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance.
      Yu J, Yan Y, Li S, Xu Y, Parolia A, Rizvi S, Wang W, Zhai Y, Xiao R, Li X, Liao P, Zhou J, Okla K, Lin H, Lin X, Grove S, Wei S, Vatan L, Hu J, Szumilo J, Kotarski J, Freeman ZT, Skala S, Wicha M, Cho KR, Chinnaiyan AM, Schon S, Wen F, Kryczek I, Wang S, Chen L, Zou W. Cell, 2024 Aug 22; 187 (17): 4713 - 4732.e19. DOI:10.1016/j.cell.2024.06.012
      PMID: 38968937
    • Journal Article
      Performance analysis of REST API technologies using Spring and Express.js examples
      Wicha M, Pańczyk B. Journal of Computer Sciences Institute, 29: 352 - 359. DOI:10.35784/jcsi.3796
    • Journal Article
      The BET degrader ZBC260 suppresses stemness and tumorigenesis and promotes differentiation in triple-negative breast cancer by disrupting inflammatory signaling.
      Sharma D, Hager CG, Shang L, Tran L, Zhu Y, Ma A, Magnuson B, Lesko MW, Wicha MS, Burness ML. Breast Cancer Res, 2023 Nov 15; 25 (1): 144 DOI:10.1186/s13058-023-01715-3
      PMID: 37968653