Associate Professor Emerita of Biological Chemistry
[email protected]
Available to mentor
Ruthann Nichols
Associate Professor Emeritus/a
-
Center MemberSamuel and Jean Frankel Cardiovascular Center
-
Pittala K, Nichols R, Maynard B, Leander M, Creech J, da Rocha AM, Heron T. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022 May 1; 36:Journal ArticleThe Design of an Antagonist that Improves Cardiac Function through Ligand-Directed Signaling
DOI:10.1096/fasebj.2022.36.S1.R2920 -
Nichols R, Bass C, Katanski C. Front Biosci (Landmark Ed), 2022 May 10; 27 (5): 150Journal ArticleStructure-activity relationship data and ligand-receptor interactions identify novel agonists consistent with sulfakinin tissue-specific signaling in Drosophila melanogaster heart.
DOI:10.31083/j.fbl2705150 PMID: 35638417 -
Nichols R, Pittala K, Leander M, Maynard B, Nikolaou P, Marciniak P. Peptides, 2021 Dec; 146: 170641Journal ArticleThe myosuppressin structure-activity relationship for cardiac contractility and its receptor interactions support the presence of a ligand-directed signaling pathway in heart.
DOI:10.1016/j.peptides.2021.170641 PMID: 34453985 -
Davis J, Chouman A, Creech J, Monteiro da Rocha A, Ponce-Balbuena D, Jimenez Vazquez EN, Nichols R, Lozhkin A, Madamanchi NR, Campbell KF, Herron TJ. JCI Insight, 2021 May 24; 6 (10):Journal ArticleIn vitro model of ischemic heart failure using human induced pluripotent stem cell-derived cardiomyocytes.
DOI:10.1172/jci.insight.134368 PMID: 33878037 -
Leander M, Heimonen J, Brocke T, Rasmussen M, Bass C, Palmer G, Egle J, Mispelon M, Berry K, Nichols R. Peptides, 2016 Sep; 83: 49 - 56.Journal ArticleThe 5-amino acid N-terminal extension of non-sulfated drosulfakinin II is a unique target to generate novel agonists.
DOI:10.1016/j.peptides.2016.07.002 PMID: 27397853 -
Rasmussen M, Leander M, Ons S, Nichols R. Peptides, 2015 Sep; 71: 259 - 267.Journal ArticleConserved molecular switch interactions in modeled cardioactive RF-NH2 peptide receptors: Ligand binding and activation.
DOI:10.1016/j.peptides.2015.07.012 PMID: 26211890 -
Leander M, Bass C, Marchetti K, Maynard BF, Wulff JP, Ons S, Nichols R. PLoS One, 2015 10 (3): e0120492Journal ArticleCardiac contractility structure-activity relationship and ligand-receptor interactions; the discovery of unique and novel molecular switches in myosuppressin signaling.
DOI:10.1371/journal.pone.0120492 PMID: 25793503 -
Bass C, Katanski C, Maynard B, Zurro I, Mariane E, Matta M, Loi M, Melis V, Capponi V, Muroni P, Setzu M, Nichols R. Peptides, 2014 Mar; 53: 278 - 285.Journal ArticleConserved residues in RF-NH₂ receptor models identify predicted contact sites in ligand-receptor binding.
DOI:10.1016/j.peptides.2013.06.009 PMID: 23811075
Department News
Congratulations and best wishes to Ruthann Nichols, PhD, Associate Professor Emerita of Biological Chemistry.
