Research Investigator
Internal Medicine
[email protected]
Available to mentor
Maroof M Alam
Research Investigator
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Arunagiri A, Alam M, Haataja L, Draz H, Alasad B, Samy P, Sadique N, Tong Y, Cai Y, Shakeri H, Fantuzzi F, Ibrahim H, Jang I, Sidarala V, Soleimanpour SA, Satin LS, Otonkoski T, Cnop M, Itkin-Ansari P, Kaufman RJ, Liu M, Arvan P. Protein Sci, 2024 Apr; 33 (4): e4949Journal ArticleProinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
DOI:10.1002/pro.4949 PMID: 38511500 -
Xu X, Arunagiri A, Alam M, Haataja L, Evans CR, Zhao I, Castro-Gutierrez R, Russ HA, Demangel C, Qi L, Tsai B, Liu M, Arvan P. J Biol Chem, 2023 Jul; 299 (7): 104836Journal ArticleNutrient-dependent regulation of β-cell proinsulin content.
DOI:10.1016/j.jbc.2023.104836 PMID: 37209827 -
Garg A, Alam M, Bai S, Dandawate M, Kumari N, Gupta S, Agrawal U, Nagarajan P, Reddy DS, Kulkarni MJ, Mukhopadhyay A. ACS Pharmacol Transl Sci, 2023 Feb 10; 6 (2): 253 - 269.Journal ArticleProtective Effects of Rifampicin and Its Analog Rifampicin Quinone in a Mouse Model of Obesity-Induced Type 2 Diabetes.
DOI:10.1021/acsptsci.2c00082 PMID: 36798477 -
Xu X, Arunagiri A, Haataja L, Alam M, Ji S, Qi L, Tsai B, Liu M, Arvan P. J Biol Chem, 2022 Oct; 298 (10): 102406Journal ArticleProteasomal degradation of WT proinsulin in pancreatic beta cells.
DOI:10.1016/j.jbc.2022.102406 PMID: 35988641 -
Alam M, Arunagiri A, Haataja L, Torres M, Larkin D, Kappler J, Jin N, Arvan P. Diabetes, 2022 Apr 1; 71 (4): 870Journal ArticleErratum. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes 2021;70:2580-2594.
DOI:10.2337/db22-er04a PMID: 34994789 -
Alam M, Arunagiri A, Haataja L, Torres M, Larkin D, Kappler J, Jin N, Arvan P. 2021 bioRxiv,PreprintPredisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes
DOI:10.1101/2021.06.01.446633 -
Liu M, Huang Y, Xu X, Li X, Alam M, Arunagiri A, Haataja L, Ding L, Wang S, Itkin-Ansari P, Kaufman RJ, Tsai B, Qi L, Arvan P. J Clin Invest, 2021 Jan 19; 131 (2):Journal ArticleNormal and defective pathways in biogenesis and maintenance of the insulin storage pool.
DOI:10.1172/JCI142240 PMID: 33463547 -
Alam M, Arunagiri A, Haataja L, Torres M, Larkin D, Kappler J, Jin N, Arvan P. Diabetes, 2021 Nov; 70 (11): 2580 - 2594.Proceeding / Abstract / PosterPredisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes.
DOI:10.2337/db21-0422 PMID: 34462258