Sonya J Wolf-Fortune
Assistant Professor of Pharmacology
Pharmacology
1150 W Medical Center Dr, MSRBIII 1301B
Ann Arbor, Michigan 48103
[email protected]

Available to mentor
Sonya J Wolf-Fortune
Assistant Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
    • Qualifications
    • Postdoctoral Fellow
      University of Michigan Medical School, Ann Arbor, 2024
    • PhD
      University of Michigan Medical School, Ann Arbor, 2019
    • BS
      Prairie View A&M University, Prairie View, 2013
    Center Memberships
    • Center Member
      Caswell Diabetes Institute
    Research Overview

    The Wolf-Fortune lab aims understand the molecular mechanisms linking chronic skin inflammatory conditions, such as psoriasis, and metabolic dysfunction. We have a particular interest in studying epigenetic regulation and structural-immune cell crosstalk. This work will provide new mechanistic insights for novel therapeutic intervention for patients with chronic skin inflammatory conditions and type 2 diabetes.

    Recent Publications See All Publications
    • Journal Article
      416 Epigenetic regulation of keratinocyte-mediated IFN kappa expression in IMQ-induced psoriasis
      Wolf-Fortune S, Joshi A, Moon J, Mangum K, Bauer T, Shadiow J, Gudjonsson JE, Kahlenberg M, Gallagher K. Journal of Investigative Dermatology, 2024 Aug; 144 (8): s72 DOI:10.1016/j.jid.2024.06.432
    • Proceeding / Abstract / Poster
      The Histone Demethylase JMJD3 Regulates Smooth Muscle Cell Phenotype during Macrophage-mediated Inflammation
      Mangum KD, Bauer T, Joshi A, Wolf-Fortune S, Moon J, Li Q, Gudjonsson J, Obi A, Davis F, Gallagher K. Journal of Vascular Surgery, 2024 Jun; 79 (6): e292 DOI:10.1016/j.jvs.2024.03.376
    • Presentation
      Examining the chronic skin inflammation-diabetes axis
      Wolf-Fortune S. 2023 Sep;
    • Journal Article
      29-OR: Diabetic Wound Keratinocytes Induce Macrophage JMJD3–Mediated Nlrp3 Expression
      WOLF-FORTUNE S, MOON J, JOSHI A, MAZUMDER P, BARRETT E, MANGUM KD, GALLAGHER K. Diabetes, 2023 Jun 20; 72 (Supplement_1): DOI:10.2337/db23-29-or
    • Proceeding / Abstract / Poster
      458-P: Proinflammatory Macrophage Phenotype Modulates Vascular Smooth Muscle Cell Differentiation via the Histone Demethylase JMJD3
      MANGUM KD, JOSHI A, MAZUMDER P, WOLF-FORTUNE S, BARRETT E, MOORE B, DAVIS FM, GALLAGHER K. Diabetes, 2023 Jun 20; 72 (Supplement_1): DOI:10.2337/db23-458-p
    • Presentation
      Dysregulation of keratinocyte/macrophage axis in obesity driven diabetic wounds​
      Wolf-Fortune S. 2023 May;
    • Journal Article
      Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair.
      Audu CO, Melvin WJ, Joshi AD, Wolf SJ, Moon JY, Davis FM, Barrett EC, Mangum KD, Deng H, Xing X, Wasikowski R, Tsoi LC, Sharma SB, Bauer TM, Shadiow J, Corriere MA, Obi AT, Kunkel SL, Levi B, Moore BB, Gudjonsson JE, Smith AM, Gallagher KA. Cell Mol Immunol, 2022 Nov; 19 (11): 1251 - 1262. DOI:10.1038/s41423-022-00919-5
      PMID: 36127466
    • Journal Article
      IFN-κ is critical for normal wound repair and is decreased in diabetic wounds.
      Wolf SJ, Audu CO, Joshi A, denDekker A, Melvin WJ, Davis FM, Xing X, Wasikowski R, Tsoi LC, Kunkel SL, Gudjonsson JE, O'Riordan MX, Kahlenberg JM, Gallagher KA. JCI Insight, 2022 May 9; 7 (9): DOI:10.1172/jci.insight.152765
      PMID: 35358091