Yang Yue, PhD
Assistant Research Scientist, Cell and Developmental Biology
[email protected]

Available to mentor

Yang Yue, PhD
Assistant Research Scientist
  • Research Overview
  • Recent Publications
  • Research Overview

    1. Investigating the mechanical properties and regulatory mechanisms of kinesin motors in intracellular transport.
    2. Exploring the interplay between kinesin motors and microtubule lattices.
    3. Developing probes for studying the post-translational modifications of microtubules and their regulatory mechanisms.
    4. Analyzing the mechanisms that regulate microtubule stability.
    5. Examining the roles of kinesin motors and microtubule post-translational modifications in neuronal functions.

    Recent Publications See All Publications
    • Journal Article
      Poxvirus A51R Proteins Negatively Regulate Microtubule-Dependent Transport by Kinesin-1.
      Seo D, Yue Y, Yamazaki S, Verhey KJ, Gammon DB. Int J Mol Sci, 2024 Jul 17; 25 (14): DOI:10.3390/ijms25147825
      PMID: 39063067
    • Journal Article
      Motor protein Kif6 regulates cilia motility and polarity in brain ependymal cells.
      Takagishi M, Yue Y, Gray RS, Verhey KJ, Wallingford JB. Dis Model Mech, 2024 Feb 1; 17 (2): DOI:10.1242/dmm.050137
      PMID: 38235522
    • Journal Article
      Autoinhibited kinesin-1 adopts a hierarchical folding pattern
      Tan Z, Yue Y, Leprevost F, Haynes S, Basrur V, Nesvizhskii AI, Verhey KJ, Cianfrocco MA. eLife, 12: DOI:10.7554/elife.86776.3
    • Journal Article
      Microtubule detyrosination by VASH1/SVBP is regulated by the conformational state of tubulin in the lattice.
      Yue Y, Hotta T, Higaki T, Verhey KJ, Ohi R. Curr Biol, 2023 Oct 9; 33 (19): 4111 - 4123.e7. DOI:10.1016/j.cub.2023.07.062
      PMID: 37716348
    • Journal Article
      Temperature-dependent RNA editing in octopus extensively recodes the neural proteome.
      Birk MA, Liscovitch-Brauer N, Dominguez MJ, McNeme S, Yue Y, Hoff JD, Twersky I, Verhey KJ, Sutton RB, Eisenberg E, Rosenthal JJC. Cell, 2023 Jun 8; 186 (12): 2544 - 2555.e13. DOI:10.1016/j.cell.2023.05.004
      PMID: 37295402
    • Journal Article
      Kif9 is an active kinesin motor required for ciliary beating and proximodistal patterning of motile axonemes.
      Konjikusic MJ, Lee C, Yue Y, Shrestha BD, Nguimtsop AM, Horani A, Brody S, Prakash VN, Gray RS, Verhey KJ, Wallingford JB. J Cell Sci, 2023 Mar 1; 136 (5): DOI:10.1242/jcs.259535
      PMID: 35531639
    • Preprint
      Kif6 regulates cilia motility and polarity in brain ependymal cells.
      Takagishi M, Yue Y, Gray RS, Verhey KJ, Wallingford JB. 2023 Feb 16; DOI:10.1101/2023.02.15.528715
      PMID: 36824804
    • Proceeding / Abstract / Poster
      A novel probe illuminates the chemical logic of microtubule detyrosination
      Yue Y, Hotta T, Verhey KJ, Ohi R. MOLECULAR BIOLOGY OF THE CELL, 2023 34 (2): 373 - 373.