Assistant Research Scientist, Cell and Developmental Biology
[email protected]
Available to mentor
Yang Yue, PhD
Assistant Research Scientist
1. Investigating the mechanical properties and regulatory mechanisms of kinesin motors in intracellular transport.
2. Exploring the interplay between kinesin motors and microtubule lattices.
3. Developing probes for studying the post-translational modifications of microtubules and their regulatory mechanisms.
4. Analyzing the mechanisms that regulate microtubule stability.
5. Examining the roles of kinesin motors and microtubule post-translational modifications in neuronal functions.
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Seo D, Yue Y, Yamazaki S, Verhey KJ, Gammon DB. Int J Mol Sci, 2024 Jul 17; 25 (14):Journal ArticlePoxvirus A51R Proteins Negatively Regulate Microtubule-Dependent Transport by Kinesin-1.
DOI:10.3390/ijms25147825 PMID: 39063067 -
Takagishi M, Yue Y, Gray RS, Verhey KJ, Wallingford JB. Dis Model Mech, 2024 Feb 1; 17 (2):Journal ArticleMotor protein Kif6 regulates cilia motility and polarity in brain ependymal cells.
DOI:10.1242/dmm.050137 PMID: 38235522 -
Tan Z, Yue Y, Leprevost F, Haynes S, Basrur V, Nesvizhskii AI, Verhey KJ, Cianfrocco MA. eLife, 12:Journal ArticleAutoinhibited kinesin-1 adopts a hierarchical folding pattern
DOI:10.7554/elife.86776.3 -
Yue Y, Hotta T, Higaki T, Verhey KJ, Ohi R. Curr Biol, 2023 Oct 9; 33 (19): 4111 - 4123.e7.Journal ArticleMicrotubule detyrosination by VASH1/SVBP is regulated by the conformational state of tubulin in the lattice.
DOI:10.1016/j.cub.2023.07.062 PMID: 37716348 -
Birk MA, Liscovitch-Brauer N, Dominguez MJ, McNeme S, Yue Y, Hoff JD, Twersky I, Verhey KJ, Sutton RB, Eisenberg E, Rosenthal JJC. Cell, 2023 Jun 8; 186 (12): 2544 - 2555.e13.Journal ArticleTemperature-dependent RNA editing in octopus extensively recodes the neural proteome.
DOI:10.1016/j.cell.2023.05.004 PMID: 37295402 -
Konjikusic MJ, Lee C, Yue Y, Shrestha BD, Nguimtsop AM, Horani A, Brody S, Prakash VN, Gray RS, Verhey KJ, Wallingford JB. J Cell Sci, 2023 Mar 1; 136 (5):Journal ArticleKif9 is an active kinesin motor required for ciliary beating and proximodistal patterning of motile axonemes.
DOI:10.1242/jcs.259535 PMID: 35531639 -
Takagishi M, Yue Y, Gray RS, Verhey KJ, Wallingford JB. 2023 Feb 16;PreprintKif6 regulates cilia motility and polarity in brain ependymal cells.
DOI:10.1101/2023.02.15.528715 PMID: 36824804 -
Yue Y, Hotta T, Verhey KJ, Ohi R. MOLECULAR BIOLOGY OF THE CELL, 2023 34 (2): 373 - 373.Proceeding / Abstract / PosterA novel probe illuminates the chemical logic of microtubule detyrosination