Cagri Bodur
Research Investigator
Internal Medicine
Dept. of Internal Medicine, Div. of Metabolism, Endocrinology & Diabetes
2800 Plymouth Road B25-3743
Ann Arbor, MI 48109
[email protected]

Available to mentor
Cagri Bodur
Research Investigator
  • Qualifications
  • Center Memberships
  • Research Overview
  • Links
  • Recent Publications
    • Qualifications
    • Postdoctoral research fellow
      University of Michigan Medical School, Department of Cell and Developmental Biology, 2019
    • Postdoctoral research fellow
      Sabancı University, Molecular Biology, Genetics and Bioengineering Program, 2014
    • Ph.D.
      Middle East Technical University, Ankara, 2005
    • M.Sc.
      Middle East Technical University, Ankara, 2001
    • B.Sc.
      Middle East Technical University, Ankara, 1999
    Center Memberships
    • Center Member
      Caswell Diabetes Institute
    Research Overview

    Leptin signaling in brain in regulation of food intake and energy expenditure
    Intracellular mTOR signaling in regulation of obesity-linked inflammation and insulin resistance

    Links
    • https://scholar.google.com/citations?user=IFnMIn4AAAAJ&hl=en
    • linkedin
    Recent Publications See All Publications
    • Journal Article
      TBK1-mTOR Signaling Attenuates Obesity-Linked Hyperglycemia and Insulin Resistance.
      Bodur C, Kazyken D, Huang K, Tooley AS, Cho KW, Barnes TM, Lumeng CN, Myers MG, Fingar DC. Diabetes, 2022 Nov 1; 71 (11): 2297 - 2312. DOI:10.2337/db22-0256
      PMID: 35983955
    • Journal Article
      The innate immune kinase TBK1 directly increases mTORC2 activity and downstream signaling to Akt.
      Tooley AS, Kazyken D, Bodur C, Gonzalez IE, Fingar DC. J Biol Chem, 2021 Aug; 297 (2): 100942 DOI:10.1016/j.jbc.2021.100942
      PMID: 34245780
    • Preprint
      The innate immune kinase TBK1 directly increases mTORC2 activity and downstream signaling to Akt
      Tooley A, Kazyken D, Bodur C, Gonzalez I, Fingar D. bioRxiv, DOI:10.1101/2021.03.30.437707
    • Presentation
      Downstream Mediators of Leptin Receptor Signaling
      Bodur C. 2020 Aug 4;
    • Presentation
      TBK1 signaling to mTOR promotes immune-metabolic fitness in obesity
      Bodur C. 2019 Oct 1;
    • Journal Article
      AMPK directly activates mTORC2 to promote cell survival during acute energetic stress.
      Kazyken D, Magnuson B, Bodur C, Acosta-Jaquez HA, Zhang D, Tong X, Barnes TM, Steinl GK, Patterson NE, Altheim CH, Sharma N, Inoki K, Cartee GD, Bridges D, Yin L, Riddle SM, Fingar DC. Sci Signal, 2019 Jun 11; 12 (585): DOI:10.1126/scisignal.aav3249
      PMID: 31186373
    • Journal Article
      The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists.
      Bodur C, Kazyken D, Huang K, Ekim Ustunel B, Siroky KA, Tooley AS, Gonzalez IE, Foley DH, Acosta-Jaquez HA, Barnes TM, Steinl GK, Cho K-W, Lumeng CN, Riddle SM, Myers MG, Fingar DC. EMBO J, 2018 Jan 4; 37 (1): 19 - 38. DOI:10.15252/embj.201696164
      PMID: 29150432
    • Journal Article
      AMP-activated protein kinase couples 3-bromopyruvate-induced energy depletion to apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl-2 proteins.
      Bodur C, Karakas B, Timucin AC, Tezil T, Basaga H. Mol Carcinog, 2016 Nov; 55 (11): 1584 - 1597. DOI:10.1002/mc.22411
      PMID: 26373689