Sean Eddy
Associate Research Scientist
Internal Medicine
[email protected]

Available to mentor
Sean Eddy
Associate Research Scientist
  • Qualifications
  • Research Overview
  • Links
  • Recent Publications
    • Qualifications
    • Post Doctoral Research Associate
      Boston University School of Medicine, Biochemistry, 2008
    Research Overview

    Systems biology, bioinformatics, and computational biology of human diseases
    Precision Medicine in Kidney Disease
    Drug Repurposing Opportunities in Rare Diseases
    SARS-CoV-2 Mechanisms of Kidney Injury
    Target and Biomarker Discovery

    Links
    Recent Publications See All Publications
    • Journal Article
      WNT-dependent interaction between inflammatory fibroblasts and FOLR2+ macrophages promotes fibrosis in chronic kidney disease.
      Cohen C, Mhaidly R, Croizer H, Kieffer Y, Leclere R, Vincent-Salomon A, Robley C, Anglicheau D, Rabant M, Sannier A, Timsit M-O, Eddy S, Kretzler M, Ju W, Mechta-Grigoriou F. Nat Commun, 2024 Jan 25; 15 (1): 743 DOI:10.1038/s41467-024-44886-z
      PMID: 38272907
    • Preprint
      Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy.
      Yoon J, Liu Z, Alaba M, Bruggeman LA, Janmey PA, Arana CA, Ayenuyo O, Medeiros I, Eddy S, Kretzler M, Henderson JM, Nair V, Naik AS, Chang AN, Miller RT. 2024 Nov 17; DOI:10.1101/2024.02.26.582201
      PMID: 38948788
    • Proceeding / Abstract / Poster
      An Omnibus of Transcripts Integrated from More than One Million Nuclei and Cells of Patients with Kidney Diseases Provides Distinct Insights into Disease Mechanisms
      McCown PJ, Otto EA, Fermin D, Hartman JR, Alaba MO, Larkina M, Arbit M, Helmuth M, Godfrey BA, Eddy S, Mariani LH, Naik AS, Hoek M, Satterfield T, Kretzler M. Journal of the American Society of Nephrology, 2024 Oct; 35 (10S): 10.1681/asn.2024thq273wq - 10.1681/asn.2024thq273wq. DOI:10.1681/asn.2024thq273wq
    • Journal Article
      Autophagy-Related Gene Expression in Diabetes and CKD
      Limonte CP, Eddy S, Gharib S, Alpers CE, Barisoni L, Menon R, Nair V, Rosas SE, Poggio ED, De Boer I. Journal of the American Society of Nephrology, 2024 Oct; 35 (10S): 10.1681/asn.2024kvvct9pn DOI:10.1681/asn.2024kvvct9pn
    • Journal Article
      Dissecting Deregulated Multicellular Programs in IgA Nephropathy
      Boys CM, McCown PJ, Eddy S, Kretzler M, Saez-Rodriguez J. Journal of the American Society of Nephrology, 2024 Oct; 35 (10S): 10.1681/asn.2024hqyrpdwx DOI:10.1681/asn.2024hqyrpdwx
    • Journal Article
      Identification of Kidney Cell Types in Single-Cell RNA Sequencing and Single-Nucleus RNA Sequencing Data Using Machine-Learning Algorithms
      Madapoosi SS, Tisch A, Blough SA, Rosa JS, Eddy S, Naik AS, Limonte CP, McCown PJ, Menon R, Rosas SE, Parikh CR, Mariani LH, Kretzler M, Mahfouz A, Alakwaa F. Journal of the American Society of Nephrology, 2024 Oct; 35 (10S): 10.1681/asn.2024qx0f9jkh - 10.1681/asn.2024qx0f9jkh. DOI:10.1681/asn.2024qx0f9jkh
    • Journal Article
      Predicting Calcineurin Inhibitor Response in Glomerular Diseases
      Eddy S, Helmuth M, McCown PJ, Nair V, Boys CM, Hartman JR, Larkina M, Ju W, Saez-Rodriguez J, Mariani LH, Kretzler M. Journal of the American Society of Nephrology, 2024 Oct; 35 (10S): 10.1681/asn.2024t4wfszbh DOI:10.1681/asn.2024t4wfszbh
    • Journal Article
      Urinary TNFR2 and Association with Kidney Injury in Patients with Nephrotic Syndrome
      Nair V, Lee E, Eddy S, Helmuth M, Fermin D, Chinnakotla S, Hodgin JB, Mariani LH, Kretzler M, Ju W. Journal of the American Society of Nephrology, 2024 Oct; 35 (10S): 10.1681/asn.20243996wrbn DOI:10.1681/asn.20243996wrbn