Associate Research Scientist
Internal Medicine
[email protected]
Available to mentor
Ying Feng
Associate Research Scientist
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Zhu N, Tang J, Feng Y, Green M, Zhai Y, Osher N, Baladandayuthanpani V, Hu K, Cho K, Fearon E.Journal ArticleRecurrent and dynamic spread of colorectal cancer cells underlies metastatic intra-lesion heterogeneity
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Feng Y, Zhu N, Bedi K, Li J, Green M, Perera C, Assarzadegan N, Zhai Y, Baladandayuthanpani V, Spence J, Cho K, Fearon E.Journal ArticleSOX9 is a context-dependent tumor suppressor in colon cancer development: inactivation of SOX9 promotes tumor progression via enhancing epithelial-mesenchymal transition and expression of SOX2
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Zhao Y, Zhao X, Chen V, Feng Y, Wang L, Croniger C, Conlon RA, Markowitz S, Fearon E, Puchowicz M, Brunengraber H, Hao Y, Wang Z. Sci Rep, 2019 Dec 16; 9 (1): 19180Journal ArticleColorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo.
DOI:10.1038/s41598-019-55718-2 PMID: 31844152 -
Tang J, Feng Y, Kuick R, Green M, Green M, Sakamoto N, Kurosu Y, Lin J, Cho KR, Fearon ER. Lab Invest, 2019 Oct; 99 (10): 1454 - 1469.Journal ArticleTrp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis.
DOI:10.1038/s41374-019-0269-y PMID: 31148594 -
Bashir B, Merlino DJ, Rappaport JA, Gnass E, Palazzo JP, Feng Y, Fearon ER, Snook AE, Waldman SA. Hum Pathol, 2019 May; 87: 103 - 114.Journal ArticleSilencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated, and MSI colorectal neoplasia.
DOI:10.1016/j.humpath.2018.11.032 PMID: 30716341 -
Schofield HK, Zeller J, Espinoza C, Halbrook CJ, Del Vecchio A, Magnuson B, Fabo T, Cali Daylan AE, Kovalenko I, Lee H-J, Yan W, Feng Y, Karim SA, Kremer DM, Kumar-Sinha C, Lyssiotis CA, Ljungman M, Morton JP, Galbán S, Fearon ER, Pasca di Magliano M. JCI Insight, 2018 Jan 25; 3 (2):Journal ArticleMutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma.
DOI:10.1172/jci.insight.97422 PMID: 29367463 -
Taniguchi K, Moroishi T, de JPR, Krawczyk M, Grebbin BM, Luo H, Xu RH, Golob-Schwarzl N, Schweiger C, Wang K, Di CGFY, Fearon ER, Raz E, Kenner L, Farin HF, Guan K, Haybaeck J, Datz C, Zhang K, Karin M. Proc Natl Acad Sci U S A, 2017 Feb 14; 114 (7): 1643 - 1648.Journal ArticleYAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.
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Sakamoto N, Feng Y, Stolfi C, Kurosu Y, Green M, Lin J, Green ME, Sentani K, Yasui W, McMahon M, Hardiman KM, Spence JR, Horita N, Greenson JK, Kuick R, Cho KR, Fearon ER. Elife, 2017 Jan 10; 6:Journal ArticleBRAFV600E cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis.
DOI:10.7554/eLife.20331 PMID: 28072391
