Assistant Professor of Pharmacology
Pharmacology
1220A MSRB3, 1150 W Medical Center Dr.
Ann Arbor, MI 48109
[email protected]
1220A MSRB3, 1150 W Medical Center Dr.
Ann Arbor, MI 48109
Available to mentor
Kyoung E Lee
Assistant Professor
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Postdoctoral FellowUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, 2018
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PhDNew York University School of Medicine, New York, 2010
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BSKorea Advanced Institute of Science and Technology (KAIST), Daejeon, 2003
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Center MemberRogel Cancer Center
Role of hypoxia in pancreatic tumorigenesis
Lab Website
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Oh J-M, Kim Y, Lee HS, Son H, Heo HJ, Baek SE, Kim EK, Lee J-Y, Lee KE, Kim YH, Kim H-J. J Dent, 2024 Dec; 151: 105366Journal ArticlePaired transcriptional analysis of periodontitis and peri-implantitis within same host: A pilot study.
DOI:10.1016/j.jdent.2024.105366 PMID: 39357620 -
Lee KE, Pasca di Magliano M. Cancer Immunol Res, 2024 Sep 3; 12 (9): 1130 - 1131.Journal ArticleUnveiling the Culprit: IL17 Signaling in the Pancreatic Epithelium Drives Tumorigenesis.
DOI:10.1158/2326-6066.CIR-24-0479 PMID: 38990149 -
Brown BA, Myers PJ, Adair SJ, Pitarresi JR, Sah-Teli SK, Campbell LA, Hart WS, Barbeau MC, Leong K, Seyler N, Kane W, Lee KE, Stelow E, Jones M, Simon MC, Koivunen P, Bauer TW, Stanger BZ, Lazzara MJ. Cancer Res, 2024 Jun 4; 84 (11): 1764 - 1780.Journal ArticleA Histone Methylation-MAPK Signaling Axis Drives Durable Epithelial-Mesenchymal Transition in Hypoxic Pancreatic Cancer.
DOI:10.1158/0008-5472.CAN-22-2945 PMID: 38471099 -
Jain C, Parimi S, Huang W, Hannifin S, Singhal R, Das NK, Lee KE, Shah YM. Exp Hematol, 2023 125-126: 25 - 36.e1.Journal ArticleMyeloid Hif2α is not essential to maintain systemic iron homeostasis.
DOI:10.1016/j.exphem.2023.08.001 PMID: 37562670 -
Lee KE. Am J Physiol Cell Physiol, 2023 Jan 1; 324 (1): C10 - C13.Journal ArticleHypoxia as a regulator of tumor stroma and metastasis.
DOI:10.1152/ajpcell.00158.2022 PMID: 36409179 -
Mello AM, Ngodup T, Lee Y, Donahue KL, Li J, Rao A, Carpenter ES, Crawford HC, Pasca di Magliano M, Lee KE. Oncogenesis, 2022 Sep 15; 11 (1): 56Journal ArticleHypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer.
DOI:10.1038/s41389-022-00434-2 PMID: 36109493 -
Mello A, Ngodup T, Lee Y, Donahue K, Li J, Rao A, Carpenter E, Crawford H, di Magliano MP, Lee KE. 2022 bioRxiv,PreprintHypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer
DOI:10.1101/2022.05.05.490771 -
Li F, Huangyang P, Burrows M, Guo K, Riscal R, Godfrey J, Lee KE, Lin N, Lee P, Blair IA, Keith B, Li B, Simon MC. Nat Cell Biol, 2020 Jun; 22 (6): 728 - 739.Journal ArticleFBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome.
DOI:10.1038/s41556-020-0511-2 PMID: 32367049