Research Assistant Professor
Internal Medicine
Internal Medicine
2800 Plymouth Road
Ann Arbor, MI 48109
[email protected]
2800 Plymouth Road
Ann Arbor, MI 48109
Available to mentor
Yanhong Guo
Research Assistant Professor
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Center MemberSamuel and Jean Frankel Cardiovascular Center
My studies focus on characterizing the cellular and molecular mechanisms of cardiovascular disease (CVD) relevant genes identified by human genetic studies. The long-term goal of my research program is to provide novel therapeutic targets for treating CVD.
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Wang Z, Mu W, Zhong J, Xu R, Liu Y, Zhao G, Guo Y, Zhang J, Surakka I, Chen YE, Chang L. J Clin Invest, 2024 Dec 3;Journal ArticleVascular smooth muscle cell PRDM16 regulates circadian variation in blood pressure.
DOI:10.1172/JCI183409 PMID: 39625782 -
Zhao G, Zhao Y, Liang W, Lu H, Liu H, Deng Y, Zhu T, Guo Y, Chang L, Garcia-Barrio MT, Chen YE, Zhang J. Cardiovasc Diabetol, 2024 Oct 26; 23 (1): 381Journal ArticleEndothelial KLF11 is a novel protector against diabetic atherosclerosis.
DOI:10.1186/s12933-024-02473-y PMID: 39462409 -
Liang X, Hou X, Bouhamdan M, Sun Y, Song Z, Rajagopalan C, Jiang H, Wei H-G, Song J, Yang D, Guo Y, Zhang Y, Mou H, Zhang J, Chen YE, Sun F, Jin J-P, Zhang K, Xu J. JCI Insight, 2024 Feb 15; 9 (6):Journal ArticleSotagliflozin attenuates liver-associated disorders in cystic fibrosis rabbits.
DOI:10.1172/jci.insight.165826 PMID: 38358827 -
Mizrak D, Zhao Y, Feng H, Macaulay J, Tang Y, Sultan Z, Zhao G, Guo Y, Zhang J, Yang B, Chen YE. Arterioscler Thromb Vasc Biol, 2023 Dec; 43 (12): 2285 - 2297.Journal ArticleSingle-Molecule Spatial Transcriptomics of Human Thoracic Aortic Aneurysms Uncovers Calcification-Related CARTPT-Expressing Smooth Muscle Cells.
DOI:10.1161/ATVBAHA.123.319329 PMID: 37823268 -
Zhao Y, Liu Y, Zhao G, Lu H, Liu Y, Xue C, Chang Z, Liu H, Deng Y, Liang W, Wang H, Rom O, Garcia-Barrio MT, Zhu T, Guo Y, Chang L, Lin J, Chen YE, Zhang J. Cell Rep, 2023 Oct 31; 42 (10): 113171Journal ArticleMyeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis.
DOI:10.1016/j.celrep.2023.113171 PMID: 37768825 -
Schwendeman A, Chen YE, Guo Y, Zhang J, Yuan W. 2023 May 9;PatentSynthetic high density lipoproteins for delivery of drugs, nutrients and imaging agents to prevent, image and treat cardiovascular diseases
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Zhao Y, Zhao G, Chang Z, Zhu T, Zhao Y, Lu H, Xue C, Saunders TL, Guo Y, Chang L, Chen YE, Zhang J. JCI Insight, 2023 Jul 24; 8 (14):Journal ArticleGenerating endogenous Myh11-driven Cre mice for sex-independent gene deletion in smooth muscle cells.
DOI:10.1172/jci.insight.171661 PMID: 37289544 -
Wang Z, Zhao X, Zhao G, Guo Y, Lu H, Mu W, Zhong J, Garcia-Barrio M, Zhang J, Chen YE, Chang L. JCI Insight, 2023 Jun 8; 8 (11):Journal ArticlePRDM16 deficiency in vascular smooth muscle cells aggravates abdominal aortic aneurysm.
DOI:10.1172/jci.insight.167041 PMID: 37079380
