Charles S Mayo
Clinical Professor of Radiation Oncology
Radiation Oncology - Physics
1500 East Medical Center Drive
Ann Arbor, MI 48103-5010
[email protected]

Available to mentor

Charles S Mayo
Clinical Professor
  • About
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    Dr. Mayo has over 27 years’ experience in clinical medical physics and translational research, particularly in the areas of advanced treatment planning techniques with IMRT/VMAT and in the study of normal tissue tolerances as part of the QUANTEC effort. His current interests are in the areas of health care informatics (infrastructure, standardizations, and analysis), application of statistical methods in treatment and outcomes modeling, and automation of advanced treatment planning methods. This includes enabling routine, the use of retrospective statistical models developed from prior treatment experience for all patients treated in a practice to inform decisions for subsequent patients, and extending these approaches to investigate multi-institutional experience to guide health care policy.

    Center Memberships
    • Center Member
      Institute for Healthcare Policy and Innovation
    Research Overview

    Areas of Interest:
    Development of analytics metrics and visualizations distilled from big data resources to improve practice and outcomes.
    Construction and of big data resource systems enabling aggregation of key data elements as part of routine practice.
    Use of analytics to improve quality of healthcare and to guide health care policy.

    Clinical Interests:
    Advanced treatment planning methods with VMAT/IMRT
    Development of dose response models
    Creation and use of spatial dose objects to improve treatment planning and evaluation

    Recent Publications See All Publications
    • Journal Article
      Best practice guidelines for use of reference points in radiation oncology information systems to aggregate longitudinal dosimetric data.
      Witztum A, Jourani Y, Hirata EY, McNutt T, Purdie TG, Brock KK, Hong DS, Howard ME, Krauze AV, Balter PA, Stockham AL, Covington E, Xiao Y, Popple R, Mayo CS. Pract Radiat Oncol, 2024 Nov 12; DOI:10.1016/j.prro.2024.09.016
      PMID: 39542396
    • Journal Article
      Follow-up for human papillomavirus-related oropharynx cancer concentrated on unequal symptom change (FOCUS): Prospective patient-reported outcome collection.
      Edwards DM, Gharzai LA, Wang W, Mayo C, Suresh K, Schipper M, Evans JR, Malloy K, Chinn SB, Prince M, Spector M, Shuman A, Stucken C, Swiecicki PL, Worden F, Jarema J, Henderson C, Kovach A, Brenner C, Shah JL, Mierzwa ML, Casper K. Head Neck, 2024 Nov; 46 (11): 2687 - 2698. DOI:10.1002/hed.27778
      PMID: 38680087
    • Journal Article
      Order From Chaos: The Benefits of Standardized Nomenclature in Radiation Oncology.
      Richardson SL, Bosch WR, Mayo CS, McNutt TR, Moran JM, Popple RA, Xiao Y, Covington EL. Pract Radiat Oncol, 2024 14 (6): 582 - 589. DOI:10.1016/j.prro.2024.04.002
      PMID: 38636586
    • Journal Article
      Quantifying the Risk of Technology-Driven Health Disparities in Radiation Oncology.
      Moncion A, Bryant AK, Cardenas CE, Dess KJ, Ditman MN, Mayo CS, Mierzwa ML, Paradis KC, Stanley DN, Covington EL. Pract Radiat Oncol, 2024 14 (6): e522 - e529. DOI:10.1016/j.prro.2024.06.009
      PMID: 38992491
    • Proceeding / Abstract / Poster
      Application of Standardized Tissue Repair Discount Factors to Guide Spinal Cord Dose in Reirradiation
      Nieto JD, Chang DT, Paradis KC, DuRussel E, Matuszak MM, Rosen BS, Prisciandaro JI, Matrosic C, Kashani R, Evans JR, Jackson WC, Lawrence TS, Jolly S, Mierzwa ML, Mayo C. International Journal of Radiation Oncology • Biology • Physics, 2024 Oct; 120 (2): e171 DOI:10.1016/j.ijrobp.2024.07.385
    • Proceeding / Abstract / Poster
      Novel Statistical-AI Method to Automate Discovery of Predictive Factors and Thresholds for 3 Year Survival, Dysphagia and Xerostomia for Patients with Head and Neck Cancers
      Mayo C, Su S, Rosen BS, Covington E, Zhang Z, Lawrence TS, Fuller CD, Brock KK, Shah JL, Mierzwa ML. International Journal of Radiation Oncology • Biology • Physics, 2024 Oct; 120 (2): s41 - s42. DOI:10.1016/j.ijrobp.2024.07.062
    • Additional Scholarship
      Data from A Phase II Study of Optimized Individualized Adaptive Radiation Therapy for Hepatocellular Carcinoma
      Herr DJ, Wang C, Mendiratta-Lala M, Matuszak M, Mayo CS, Cao Y, Parikh ND, Ten Haken R, Owen D, Evans JR, Stanescu T, Yan M, Dawson LA, Schipper M, Lawrence TS, Cuneo KC. 2024 Sep 16; DOI:10.1158/1078-0432.c.6861242
    • Journal Article
      A joint ESTRO and AAPM guideline for development, clinical validation and reporting of artificial intelligence models in radiation therapy.
      Hurkmans C, Bibault J-E, Brock KK, van Elmpt W, Feng M, David Fuller C, Jereczek-Fossa BA, Korreman S, Landry G, Madesta F, Mayo C, McWilliam A, Moura F, Muren LP, El Naqa I, Seuntjens J, Valentini V, Velec M. Radiother Oncol, 2024 Aug; 197: 110345 DOI:10.1016/j.radonc.2024.110345
      PMID: 38838989