Marisa Buchakjian, MD, PhD
Clinical Assistant Professor of Otolaryngology-Head and Neck Surgery
Otolaryngology - Head and Neck Surgery
1500 E. Medical Center Dr.
Ann Arbor, MI 48109

Available to mentor

Marisa Buchakjian, MD, PhD
Clinical Assistant Professor
  • About
  • Qualifications
  • Research Overview
  • Recent Publications
  • About

    Dr. Buchakjian is a surgical oncology and microvascular surgeon in the Department of Otolaryngology - Head and Neck Surgery. She completed an MD/PhD at Duke University with graduate studies in Molecular Cancer Biology, and trained as a resident and T32 postdoc at the University of Iowa. After residency she joined the University of Michigan as a Head and Neck fellow, and then returned to the University of Iowa as faculty. She was previously faculty at the University of Iowa and recently moved back to the UM to join the Head and Neck Oncology Division and work with the robust translational and basic science research group. Dr. Buchakjian's clinical interests include oral cavity, oropharynx, larynx, salivary, and skin cancers. She is trained in complex microvascular free tissue transfer as well as transoral robotic surgery. She is also a member of the Rogel Comprehensive Cancer Center in the Signaling and Tumor Microenvironment Program.

    Qualifications
    • Fellow
      University of Michigan Medical School, Otolaryngology - Head and Neck Surgery
    • Resident
      University of Iowa Hospitals and Clinics, Otolaryngology - Head and Neck Surgery
    • MD/PhD
      Duke University School of Medicine, Durham
    Research Overview

    Dr. Buchakjian's research lab studies epithelial-mesenchymal transition (EMT) and invasion in oral cavity squamous cell carcinoma. She is particularly interested in alterations in metabolism and fatty acid utilization, as well as paracrine signaling mechanisms in the EMT microenvironment. Her research is primarily basic science and translational, utilizing tissue culture models, mouse models, and head and neck tumor biospecimens. She is currently funded through an Early-Stage Surgeon Scientist Program grant from the National Cancer Institute, and has received previous support from the American Cancer Society, American Academy of Otolaryngology, and Department of Defense.

    Recent Publications See All Publications
    • Journal Article
      Free Flap Outcomes for Head and Neck Surgery in Patients with COVID-19.
      Domack A, Sandelski MM, Ali S, Blackwell KE, Buchakjian M, Bur AM, Cannady SB, Castellanos CX, Ducic Y, Ghanem TA, Huang AT, Jackson RS, Kokot N, Li S, Pipkorn P, Puram SV, Rezaee R, Rajasekaran K, Shnayder Y, Sinha UK, Sukato D, Suresh N, Tamaki A, Thomas CM, Thorpe EJ, Wax MK, Yang S, Ziegler A, Pittman AL. Laryngoscope, 2024 Nov; 134 (11): 4521 - 4526. DOI:10.1002/lary.31159
      PMID: 37937733
    • Journal Article
      Correlation of Lymph Node Characteristics and Extranodal Extension in Oral Cavity Squamous Cell Carcinoma.
      Wenzel PA, Van Meeteren SL, Pagedar NA, Buchakjian MR. OTO Open, 2024 8 (4): e70032 DOI:10.1002/oto2.70032
      PMID: 39430065
    • Journal Article
      Is Preoperative Chemoprophylaxis Safe for Venous Thromboembolism Prevention in Patients With Head and Neck Cancer?
      Isaac H, Arnold MA, Pagedar NA, Buchakjian MR, Arnold KE. Otolaryngol Head Neck Surg, 2024 Oct; 171 (4): 1097 - 1105. DOI:10.1002/ohn.875
      PMID: 38943444
    • Journal Article
      Shortcomings of excisional biopsy in Early-Stage oral cavity carcinoma.
      Schemel AF, Manosalva RE, Pataroque D, Keirns D, Wagoner L, Au V, Byeman C, Renslo B, Virgen C, Sawaf T, Buchakjian M, Varvares MA, Bur AM, Holcomb AJ. Oral Oncol, 2024 Oct; 157: 106909 DOI:10.1016/j.oraloncology.2024.106909
      PMID: 39116665
    • Journal Article
      Pharyngeal Mucosal Margin Vessel Counts Predict Pharyngocutaneous Fistula in Salvage Laryngectomy.
      Prince ADP, Heft Neal ME, Buchakjian MR, Chinn SB, Stucken CL, Casper KA, Malloy KM, Prince MEP, Rosko AJ, McHugh JB, Spector ME. Otolaryngol Head Neck Surg, 2024 Sep; 171 (3): 785 - 790. DOI:10.1002/ohn.865
      PMID: 38881401
    • Journal Article
      Prognostic Role of Tumor-Infiltrating Lymphocytes in Oral Squamous Cell Carcinoma.
      Wongpattaraworakul W, Choi A, Buchakjian MR, Lanzel EA, Kd AR, Simons AL. BMC Cancer, 2024 Jun 26; 24 (1): 766 DOI:10.1186/s12885-024-12539-5
      PMID: 38926643
    • Journal Article
      Modulation of diabetic wound healing using carbon monoxide gas-entrapping materials.
      Witt E, Leach AJ, Bi J, Hatfield S, Cotoia AT, McGovern MK, Cafi AB, Rhodes AC, Cook AN, Uaroon S, Parajuli B, Kim J, Feig V, Scheiflinger A, Nwosu I, Jimenez M, Coleman MC, Buchakjian MR, Bosch DE, Tift MS, Traverso G, Otterbein LE, Byrne JD. Device, 2024 May 17; 2 (5): DOI:10.1016/j.device.2024.100320
      PMID: 38911126
    • Journal Article
      Role of Lymphovascular Invasion in Oral Cavity Squamous Cell Carcinoma Regional Metastasis and Prognosis.
      Moore AE, Alvi SA, Tarabichi O, Zhu VL, Buchakjian MR. Ann Otol Rhinol Laryngol, 2024 Mar; 133 (3): 300 - 306. DOI:10.1177/00034894231211116
      PMID: 37927046