Associate Research Scientist
Internal Medicine
[email protected]
Available to mentor
Chao-Yie Yang
Adjunct Associate Research Scientist
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Zheng C, Rej RK, Wang M, Huang L, Fernandez-Salas E, Yang C-Y, Wang S. ACS Med Chem Lett, 2023 Oct 12; 14 (10): 1389 - 1395.Journal ArticleDiscovery of Pyrrolo[2,3-c]pyridines as Potent and Reversible LSD1 Inhibitors.
DOI:10.1021/acsmedchemlett.3c00292 PMID: 37849536 -
Xiang W, Zhao L, Han X, Xu T, Kregel S, Wang M, Miao B, Qin C, Wang M, McEachern D, Lu J, Bai L, Yang C-Y, Kirchhoff PD, Takyi-Williams J, Wang L, Wen B, Sun D, Ator M, Mckean R, Chinnaiyan AM, Wang S. J Med Chem, 2023 Sep 28; 66 (18): 13280 - 13303.Journal ArticleDiscovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer.
DOI:10.1021/acs.jmedchem.3c01264 PMID: 37683104 -
Yuan X, Jiang H, Fu D, Rech JC, Robida A, Rajanayake K, Yuan H, He M, Wen B, Sun D, Liu C, Chinnaswamy K, Stuckey JA, Paczesny S, Yang C-Y. ACS Pharmacol Transl Sci, 2023 Sep 8; 6 (9): 1275 - 1287.Journal ArticleProphylactic Mitigation of Acute Graft versus Host Disease by Novel 2-(Pyrrolidin-1-ylmethyl)pyrrole-Based Stimulation-2 (ST2) Inhibitors.
DOI:10.1021/acsptsci.3c00122 PMID: 37705593 -
Swanson M, Yun J, Collier DM, Seif C, Yang C-Y, Regner KR, Park F. Am J Physiol Renal Physiol, 2023 Aug 1; 325 (2): F248 - F261.Journal ArticleIdentification of cell division cycle protein 20 in various forms of acute and chronic kidney injury in mice.
DOI:10.1152/ajprenal.00302.2022 PMID: 37348027 -
Han X, Zhao L, Xiang W, Miao B, Qin C, Wang M, Xu T, McEachern D, Lu J, Wang Y, Metwally H, Yang C-Y, Kirchhoff PD, Wang L, Matvekas A, Takyi-Williams J, Wen B, Sun D, Ator M, Mckean R, Wang S. J Med Chem, 2023 Jul 13; 66 (13): 8822 - 8843.Journal ArticleDiscovery of ARD-2051 as a Potent and Orally Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer.
DOI:10.1021/acs.jmedchem.3c00405 PMID: 37382562 -
Yuan X, Howie KL, Kazemi Sabzvar M, Chinnaswamy K, Stuckey JA, Yang C-Y. ACS Med Chem Lett, 2023 May 11; 14 (5): 681Journal ArticleCorrection to "Profiling the Binding Activities of Peptides and Inhibitors to the U2 Auxiliary Factor Homology Motif (UHM) Domains".
DOI:10.1021/acsmedchemlett.3c00123 PMID: 37197465 -
Sluter MN, Bhuniya R, Yuan X, Ramaraju A, Chen Y, Yu Y, Parmar KR, Temrikar ZH, Srivastava A, Meibohm B, Jiang J, Yang C-Y. ACS Pharmacol Transl Sci, 2023 Apr 14; 6 (4): 587 - 599.Journal ArticleNovel, Brain-Permeable, Cross-Species Benzothiazole Inhibitors of Microsomal Prostaglandin E Synthase-1 (mPGES-1) Dampen Neuroinflammation In Vitro and In Vivo.
DOI:10.1021/acsptsci.2c00241 PMID: 37082746 -
Yuan X, Howie KL, Kazemi Sabzvar M, Chinnaswamy K, Stuckey JA, Yang C-Y. ACS Med Chem Lett, 2023 Apr 13; 14 (4): 450 - 457.Journal ArticleProfiling the Binding Activities of Peptides and Inhibitors to the U2 Auxiliary Factor Homology Motif (UHM) Domains.
DOI:10.1021/acsmedchemlett.2c00537 PMID: 37077390
