Available to mentor
Alejandro Velez (Lopez) is a pediatric gastroenterologist and the director of the newly established pediatric neurogastroenterology and motility program at C.S. Mott Children's Hospital within the University of Michigan Medicine system. Dr. Velez is a proud alumni of the University of Maine and the University of Vermont medical school with strong ties to both states. His medical training was completed through Montefiore Children's Hospital in Bronx, NY for his pediatric residency, and his pediatric gastroenterology fellowship through the Cincinnati Children's Hospital. Dr. Velez' special interests lie in the motility (how it moves) of the gut and the crucially important connection between the gut and the brain. As the director of the neurogastroenterology and motility program at C.S. Mott Children's Hospital, Dr. Velez hopes to establish evidence-based and cutting edge diagnostic and management modalities for primary and secondary disorders of gut motility, and disorders of gut-brain interaction (DGBI).
Dr. Velez's interests primarily span the realms of clinical and translational research types involving the management., etiology and impact of severe chronic constipation, adapting motility testing to pediatric disorders, and the diagnosis and management of chronic, debilitating functional abdominal pain.
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Velez A, Kaul A, El-Chammas KI, Knowlton L, Madis E, Sahay R, Fei L, Stiehl S, Santucci NR. Paediatr Drugs, 2024 Jan 4;Journal ArticleSafety and Effectiveness of Prucalopride in Children with Functional Constipation with and without Upper Symptoms.
DOI:10.1007/s40272-023-00612-8 PMID: 38175354 -
Velez Lopez A, Waddell A, Antonacci S, Castillo D, Santucci N, Ollberding NJ, Eshleman EM, Denson LA, Alenghat T. Neurogastroenterol Motil, 2023 Dec; 35 (12): e14681Journal ArticleMicrobiota-derived butyrate dampens linaclotide stimulation of the guanylate cyclase C pathway in patient-derived colonoids.
DOI:10.1111/nmo.14681 PMID: 37736865 -
Shim J, Kennedy RH, Weatherly LM, Hutchinson LM, Pelletier JH, Hashmi HN, Blais K, Velez A, Gosse JA. J Appl Toxicol, 2016 Nov; 36 (11): 1446 - 1459.Journal ArticleArsenic inhibits mast cell degranulation via suppression of early tyrosine phosphorylation events.
DOI:10.1002/jat.3300 PMID: 27018130 -
Palmer RK, Hutchinson LM, Burpee BT, Tupper EJ, Pelletier JH, Kormendy Z, Hopke AR, Malay ET, Evans BL, Velez A, Gosse JA. Toxicol Appl Pharmacol, 2012 Jan 1; 258 (1): 99 - 108.Journal ArticleAntibacterial agent triclosan suppresses RBL-2H3 mast cell function.
DOI:10.1016/j.taap.2011.10.012 PMID: 22036726