Alejandro Velez
Assistant Professor of Pediatrics
[email protected]

Available to mentor

Alejandro Velez
Clinical Assistant Professor
  • About
  • Research Overview
  • Recent Publications
  • About

    Alejandro Velez (Lopez) is a pediatric gastroenterologist and the director of the newly established pediatric neurogastroenterology and motility program at C.S. Mott Children's Hospital within the University of Michigan Medicine system. Dr. Velez is a proud alumni of the University of Maine and the University of Vermont medical school with strong ties to both states. His medical training was completed through Montefiore Children's Hospital in Bronx, NY for his pediatric residency, and his pediatric gastroenterology fellowship through the Cincinnati Children's Hospital. Dr. Velez' special interests lie in the motility (how it moves) of the gut and the crucially important connection between the gut and the brain. As the director of the neurogastroenterology and motility program at C.S. Mott Children's Hospital, Dr. Velez hopes to establish evidence-based and cutting edge diagnostic and management modalities for primary and secondary disorders of gut motility, and disorders of gut-brain interaction (DGBI).

    Research Overview

    Dr. Velez's interests primarily span the realms of clinical and translational research types involving the management., etiology and impact of severe chronic constipation, adapting motility testing to pediatric disorders, and the diagnosis and management of chronic, debilitating functional abdominal pain.

    Recent Publications See All Publications
    • Journal Article
      Safety and Effectiveness of Prucalopride in Children with Functional Constipation with and without Upper Symptoms.
      Velez A, Kaul A, El-Chammas KI, Knowlton L, Madis E, Sahay R, Fei L, Stiehl S, Santucci NR. Paediatr Drugs, 2024 Jan 4; DOI:10.1007/s40272-023-00612-8
      PMID: 38175354
    • Journal Article
      Microbiota-derived butyrate dampens linaclotide stimulation of the guanylate cyclase C pathway in patient-derived colonoids.
      Velez Lopez A, Waddell A, Antonacci S, Castillo D, Santucci N, Ollberding NJ, Eshleman EM, Denson LA, Alenghat T. Neurogastroenterol Motil, 2023 Dec; 35 (12): e14681 DOI:10.1111/nmo.14681
      PMID: 37736865
    • Journal Article
      Arsenic inhibits mast cell degranulation via suppression of early tyrosine phosphorylation events.
      Shim J, Kennedy RH, Weatherly LM, Hutchinson LM, Pelletier JH, Hashmi HN, Blais K, Velez A, Gosse JA. J Appl Toxicol, 2016 Nov; 36 (11): 1446 - 1459. DOI:10.1002/jat.3300
      PMID: 27018130
    • Journal Article
      Antibacterial agent triclosan suppresses RBL-2H3 mast cell function.
      Palmer RK, Hutchinson LM, Burpee BT, Tupper EJ, Pelletier JH, Kormendy Z, Hopke AR, Malay ET, Evans BL, Velez A, Gosse JA. Toxicol Appl Pharmacol, 2012 Jan 1; 258 (1): 99 - 108. DOI:10.1016/j.taap.2011.10.012
      PMID: 22036726