Research Investigator
Internal Medicine
1000 Wall street, Brehm tower, Rm 5410
Ann Arbor
Michigan, 48105-1986 United States
[email protected]
Ann Arbor
Michigan, 48105-1986 United States
Available to mentor
Xiaohan Zhang
Research Investigator
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Postdoctoral Research FellowUniversity of Michigan, Internal Medicine
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PhDShandong University, Jinan, 2018
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Bachelor of Medicine in MedicineShandong University, Jinan, 2013
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Zhang X, Young C, Liao X-H, Refetoff S, Torres M, Tomer Y, Stefan-Lifshitz M, Zhang H, Larkin D, Fang D, Qi L, Arvan P. JCI Insight, 2023 Jun 22; 8 (12):Journal ArticlePerturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland.
DOI:10.1172/jci.insight.169937 PMID: 37345654 -
Zhang X, Young C, Morishita Y, Kim K, Kabil OO, Clarke OB, Di Jeso B, Arvan P. Int J Mol Sci, 2022 Nov 6; 23 (21):Journal ArticleDefective Thyroglobulin: Cell Biology of Disease.
DOI:10.3390/ijms232113605 PMID: 36362390 -
Zhang X, Malik B, Young C, Zhang H, Larkin D, Liao X-H, Refetoff S, Liu M, Arvan P. J Biol Chem, 2022 Jul; 298 (7): 102066Journal ArticleMaintaining the thyroid gland in mutant thyroglobulin-induced hypothyroidism requires thyroid cell proliferation that must continue in adulthood.
DOI:10.1016/j.jbc.2022.102066 PMID: 35618019 -
Zhang X, Kellogg AP, Citterio CE, Zhang H, Larkin D, Morishita Y, Targovnik HM, Balbi VA, Arvan P. JCI Insight, 2021 Jun 8; 2021 Jun 8;6(11):e148496:Journal ArticleThyroid hormone synthesis continues despite biallelic thyroglobulin mutation with cell death
DOI:10.1172/jci.insight.148496 -
Hu B, Zhao M, Luo D, Yu C, Shao S, Zhao L, Yang Y, Zhang X, Zhao J, Gao L. Int J Endocrinol, 2020 2020: 3240198Journal ArticleQuantitative Analysis of the Proteome and the Succinylome in the Thyroid Tissue of High-Fat Diet-Induced Hypothyroxinemia in Rats.
DOI:10.1155/2020/3240198 PMID: 32774361 -
Zhang X, Shao S, Zhao L, Yang R, Zhao M, Fang L, Li M, Chen W, Song Y, Xu C, Zhou X, Zhao J, Gao L. Am J Physiol Endocrinol Metab, 2019 Mar 1; 316 (3): E510 - E518.Journal ArticleER stress contributes to high-fat diet-induced decrease of thyroglobulin and hypothyroidism.
DOI:10.1152/ajpendo.00194.2018 PMID: 30620634 -
Zhao M, Zhang X, Gao L, Song Y, Xu C, Yu C, Shao S, Zhao J. Int J Endocrinol, 2018 2018: 4215848Journal ArticlePalmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Affects Thyroid?
DOI:10.1155/2018/4215848 PMID: 30416522 -
Zhang X, Chen W, Shao S, Xu G, Song Y, Xu C, Gao L, Hu C, Zhao J. Mol Nutr Food Res, 2018 Mar; 62 (6): e1700599Journal ArticleA High-Fat Diet Rich in Saturated and Mono-Unsaturated Fatty Acids Induces Disturbance of Thyroid Lipid Profile and Hypothyroxinemia in Male Rats.
DOI:10.1002/mnfr.201700599 PMID: 29363248
